Log of Annotation Updates

41 annotation updates returned
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Date Locus Tag Strain Description Submitter
Jul 16, 2006 PA5485 Pseudomonas aeruginosa PAO1 New gene name: ampDh2. New product name: AmpDh2 (changed from conserved hypothetical protein). New product name rating: Class 1. New PseudoCAP function class: Antibiotic resistance and susceptibility. Removed PseudoCAP function class: Hypothetical, unclassified, unknown. New homology: 27% identical to AmpD [Pseudomonas aeruginosa]. New evidence reference (PubMed ID): 16641450. Literature review. Approved by reference author Antonio Oliver, Servicio de Microbiologia, Palma de Mallorca, Spain
Jul 16, 2006 PA0807 Pseudomonas aeruginosa PAO1 New gene name: ampDh3. New product name: AmpDh3 (changed from conserved hypothetical protein). New product name rating: Class 1. New PseudoCAP function class: Antibiotic resistance and susceptibility. Removed PseudoCAP function class: Hypothetical, unclassified, unknown. New homology: 25% identical to AmpD [Pseudomonas aeruginosa]. New evidence reference (PubMed ID): 16641450. Literature review. Approved by reference author Antonio Oliver, Servicio de Microbiologia, Palma de Mallorca, Spain
Jul 16, 2006 PA1024 Pseudomonas aeruginosa PAO1 New product name: 2-Nitropropane Dioxygenase (changed from hypothetical protein). New product name rating: Class 1. New pathway: Nitrogen metabolism. New E.C. number: 1.13.11.32. New homology: 23% sequence identity to 2-nitropropane dioxygenase [Neurospora crassa]. New evidence reference (PubMed ID): 16682407. Literature review. Approved by reference author Se Won Suh, Seoul National University, Seoul, Korea.
Jul 16, 2006 PA2570 Pseudomonas aeruginosa PAO1 New gene name: lecA (changed from pa1L) . New product name: LecA (changed from PA-I galactophilic lectin). New alternate gene name: pa1L. New alternate product name: PA-I galactophilic lectin. New PseudoCAP function class: Cell wall / LPS / capsule. New evidence reference (PubMed ID): 16689730. Literature review. Approved by reference author Steve Diggle, University of Nottingham, Nottingham, UK
Jul 16, 2006 PA4501 Pseudomonas aeruginosa PAO1 New gene name: opdP (previously blank). Removed alternate gene name of opdP. New product name: Glycine-glutamate dipeptide porin OpdP (previously named probable porin). New product name rating: Class 1 (previous product name rating was Class 3). New subcellular localization confidence: Class 1 (previous localization confidence was Class 2). New evidence reference for subcellular localization (PMID): 16790014 New evidence reference(PMID): 16352820. New PseudoCAP function class:Membrane proteins. Literature review. Approved by reference authors Sandeep Tamber and Bob Hancock, University of British Columbia
Jul 16, 2006 PA0755 Pseudomonas aeruginosa PAO1 New gene name: opdH (previously blank). Removed alternate gene name of opdH. New product name: cis-aconitate porin OpdH (previously named probable porin). New product name rating: Class 1 (previous product name rating was Class 3). New subcellular localization confidence: Class 1 (previous localization confidence was Class 2). New evidence reference(PMID): 16352820. Sandeep Tamber and Bob Hancock, University of British Columbia
Jul 16, 2006 PA2700 Pseudomonas aeruginosa PAO1 New gene name: opdB (previously blank). Removed alternate gene name of opdB. New product name: OpdB proline porin (previously named probable porin). New product name rating: Class 1 (previous product name rating was Class 3). New evidence reference(PMID): 16352820. Sandeep Tamber and Bob Hancock, University of British Columbia
Jul 16, 2006 PA0162 Pseudomonas aeruginosa PAO1 New gene name: opdC (previously blank). Removed alternate gene name of opdC. New product name: histidine porin OpdC (previously named probable porin). New product name rating: Class 1 (previous product name rating was Class 3). New evidence reference(PMID): 16352820. Sandeep Tamber and Bob Hancock, University of British Columbia
Jul 16, 2006 PA2113 Pseudomonas aeruginosa PAO1 New gene name: opdO (previously blank). Removed alternate gene name of opdO. New product name: pyroglutatmate porin OpdO (previously named probable porin). New product name rating: Class 1 (previous product name rating was Class 3). New PseudoCAP function class: Membrane proteins. New evidence reference(PMID): 16352820. Sandeep Tamber and Bob Hancock, University of British Columbia
Jul 16, 2006 PA4898 Pseudomonas aeruginosa PAO1 New gene name: opdK (previously blank). Removed alternate gene name of opdK. New product name: vanillate porin OpdK (previously named probable porin). New product name rating: Class 1 (previous product name rating was Class 3). New evidence reference(PMID): 16352820. Sandeep Tamber and Bob Hancock, University of British Columbia
Jul 16, 2006 PA2505 Pseudomonas aeruginosa PAO1 New gene name: opdT (previously blank). New product name: tyrosine porin OpdT (previously named probable porin). New product name rating: Class 1 (previous product name rating was Class 3). New PseudoCAP function class: Membrane proteins. New evidence reference(PMID): 16352820. Sandeep Tamber and Bob Hancock, University of British Columbia
Jul 16, 2006 PA4897 Pseudomonas aeruginosa PAO1 New comment: transcription induced by vanillate. New evidence reference(PMID): 16352820. Sandeep Tamber and Bob Hancock, University of British Columbia
Jul 16, 2006 PA4899 Pseudomonas aeruginosa PAO1 New comment: transcription induced by vanillate. New evidence reference(PMID): 16352820. Sandeep Tamber and Bob Hancock, University of British Columbia
Jul 16, 2006 PA4900 Pseudomonas aeruginosa PAO1 New comment: transcription induced by vanillate. New evidence reference(PMID): 16352820. Sandeep Tamber and Bob Hancock, University of British Columbia
Jul 16, 2006 PA4901 Pseudomonas aeruginosa PAO1 New comment: transcription induced by vanillate. New evidence reference(PMID): 16352820. Sandeep Tamber and Bob Hancock, University of British Columbia
Jul 16, 2006 PA4902 Pseudomonas aeruginosa PAO1 New comment: transcription induced by vanillate. New evidence reference(PMID): 16352820. Sandeep Tamber and Bob Hancock, University of British Columbia
Jul 16, 2006 PA4903 Pseudomonas aeruginosa PAO1 New comment: transcription induced by vanillate. New evidence reference(PMID): 16352820. Sandeep Tamber and Bob Hancock, University of British Columbia
Jul 16, 2006 PA5497 Pseudomonas aeruginosa PAO1 New gene name: nrdJa. New product name: NrdJa (changed from hypothetical protein). New product name rating: Class 1 (originally Class 4). New PseudoCAP function class: Nucleotide biosynthesis and metabolism. Removed PseudoCAP function class: Hypothetical, unclassified, unknown. New comment: nrdJa and nrdJb are the subunits that form a functional Class II ribonucleotide reductase. New genomic context: part of the nrdJab operon. New evidence reference (PubMed ID): 15722359. Literature review. Approved by reference author Britt-Marie Sjoberg , Stockholm University, Sweden
Jul 16, 2006 PA5496 Pseudomonas aeruginosa PAO1 New gene name: nrdJb. New product name: NrdJb (changed from hypothetical protein). New product name rating: Class 1 (originally Class 4). New PseudoCAP function class: Nucleotide biosynthesis and metabolism. Removed PseudoCAP function class: Hypothetical, unclassified, unknown. New comment: nrdJa and nrdJb are the subunits that form a functional Class II ribonucleotide reductase. New genomic context: part of the nrdJab operon. New evidence reference (PubMed ID): 15722359. Literature review. Approved by reference author Britt-Marie Sjoberg , Stockholm University, Sweden
Jul 16, 2006 PA1156 Pseudomonas aeruginosa PAO1 New product name: NrdA, catalytic component of class Ia ribonucleotide reductase . New product name rating: Class 1 (originally Class 2). New evidence reference (PubMed ID): 16829681. Britt-Marie Sjoberg, Stockholm University, Sweden
Jul 16, 2006 PA1155 Pseudomonas aeruginosa PAO1 New product name: NrdB, tyrosyl radical-harboring component of class Ia ribonucleotide reductase. New product name rating: Class 1 (originally Class 2). New evidence reference (PubMed ID): 16829681. Britt-Marie Sjoberg, Stockholm University, Sweden
Jul 16, 2006 PA3542 Pseudomonas aeruginosa PAO1 New subcellular localization: Periplasmic (previous localization was cytoplasmic membrane). New subcellular localization confidence: Class 1 (previous localization confidence was Class 3 ). New evidence reference (PubMed ID): 16797016. Literature review. Approved by reference author Bernd Rehm, Institute of Molecular BioSciences, New Zealand.
Jul 16, 2006 PA1032 Pseudomonas aeruginosa PAO1 New gene name: quiP (previously blank). New product name: QuiP (changed from "probable penicillin amidase"). New product name rating: Class 1 (originally Class 3). New PseudoCAP function class: Carbon compound catabolism. New comment: quiP encodes a protein with acyl-HSL acylase activity for long but not short acyl-HSLs. New evidence reference (PubMed ID): 16461666. Literature review. Approved by reference author Jared R. Leadbetter , California Institute of Technology, USA
Jul 16, 2006 PA0740 Pseudomonas aeruginosa PAO1 New gene name: sdsA1 (previously blank). New product name: SDS hydrolase SdsA1 (changed from probable beta-lactamase). New product name confidence: Class 1 (previously Class 3). New evidence reference: PMID: 16684886. New subcellular localization: Extracellular (previously designated as unknown). New subcellular localization confidence: Class 1 (previously designated Class 3). New structure feature: N-terminal metallo-beta-lactamase-like domain (residues 1-379). New structure feature: alpha-helical dimerization domain (residues 380–520). New structure feature: SdsA1 is a symmetric dimer. Literature review. Approved by reference author Wolf-Dieter Schubert, German Research Centre for Biotechnology (GBF), Germany
Jul 16, 2006 PA4293 Pseudomonas aeruginosa PAO1 New gene name: pprA (previously blank). New product name: two-component sensor PprA (previously designated "probable two-component sensor"). New product name confidence: Class 1 (Previously class 3). New PseudoCAP function class: Antibiotic resistance and susceptibility. New evidence reference: PMID: 12499175. Literature review. Approved by reference author Shouguang Jin, Department of Molecular Genetics and Microbiology, University of Florida, USA
Jul 16, 2006 PA4296 Pseudomonas aeruginosa PAO1 New gene name: pprB (previously blank). New product name: two-component response regulator, PprB (previously "probable two-component response regulator"). New product name confidence: Class 1 (Previously class 3). New PseudoCAP function class: Antibiotic resistance and susceptibility. New evidence reference: PMID: 12499175. Literature review. Approved by reference author Shouguang Jin, Department of Molecular Genetics and Microbiology, University of Florida, USA
Jul 16, 2006 PA2808 Pseudomonas aeruginosa PAO1 New gene name: ptrA (previously blank). New product name: New product name: repressor, PtrA (previously designated as "hypothetical protein"). New product name confidence: Class 1 (Previously class 4). New PseudoCAP function class: Transcriptional regulators. New evidence reference (PMID): 15469505. New comment: Expression of the ptrA gene is activated by CopS (PA2810) and CopR (PA2809) in response to high copper stress. Shouguang Jin, Department of Molecular Genetics and Microbiology, University of Florida, USA
Jul 16, 2006 PA2809 Pseudomonas aeruginosa PAO1 New gene name: copR (previously blank). New product name: two-component response regulator, CopR (previously designated "probable two-component response regulator"). New product name confidence: Class 1 (Previously class 3). New PseudoCAP function class: Adaptation, Protection. New evidence reference (PMID): 15469505. New comment: Mutation leads to hypersensitivity to copper-mediated toxicity. Shouguang Jin, Department of Molecular Genetics and Microbiology, University of Florida, USA
Jul 16, 2006 PA2810 Pseudomonas aeruginosa PAO1 New gene name: copS (previously blank). New product name: two-component sensor, CopS (previously designated "probable two-component sensor"). New product name confidence: Class 1 (Previously class 3). New PseudoCAP function class: Adaptation, Protection. New evidence reference (PMID): 15469505. New comment: Mutation leads to hypersensitivity to copper-mediated toxicity. Shouguang Jin, Department of Molecular Genetics and Microbiology, University of Florida, USA
Jul 16, 2006 PA0612 Pseudomonas aeruginosa PAO1 New gene name: ptrB (previously blank). New product name: New product name: repressor, PtrB (previously designated as "hypothetical protein"). New product name confidence: Class 1 (Previously class 4). New PseudoCAP function class: Transcriptional regulators. New evidence reference (PMID): 16109947. New comment: Expression of ptrB is repressed by prtR (PA0611). PrtR mediated repression of ptrB is relieved by stresses such as DNA damage. Shouguang Jin, Department of Molecular Genetics and Microbiology, University of Florida, USA
Jul 16, 2006 PA4295 Pseudomonas aeruginosa PAO1 New gene name: fppA. New product name: Flp prepilin peptidase A, FppA (previously hypothetical protein). New product name confidence: Class 1 (previously Class 4). New evidence reference (PMID): 16788194. New PseudoCAP function class: Motility and attachment. New homology: 45% similarity to OrfB [Actinobacillus actynomycetemcomitans]. New homology: 42% similarity to CpaA [Caulobacter crescentus]. New genomic context: Outside of flp-tad-rcp gene cluster (PA4297-PA4305) required for assembly of Type IVb pilin, Flp. Alain Filloux, Centre National de la Recherche Scientifique, Marseille, France
Jul 16, 2006 PA4297 Pseudomonas aeruginosa PAO1 New gene name: tadG (previously blank). New product name: TadG (previously hypothetical protein). New product name confidence: Class 2 (previously Class 4). New evidence reference (PMID): 16788194. New evidence reference (PMID): 15837433. New PseudoCAP function class: Motility and attachment. New genomic context: Part of flp-tad-rcp gene cluster (PA4297-PA4305) required for assembly of Type IVb pilin, Flp. Alain Filloux, Centre National de la Recherche Scientifique, Marseille, France
Jul 16, 2006 PA4303 Pseudomonas aeruginosa PAO1 New gene name: tadZ (previously blank). New product name: TadZ (previously designated hypothetical protein). New product name confidence: Class 2 (previously Class 3). New evidence reference (PMID): 16788194. New evidence reference (PMID): 15837433. New PseudoCAP function class: Motility and attachment. New genomic context: Part of flp-tad-rcp gene cluster (PA4297-PA4305) required for assembly of Type IVb pilin, Flp. New homology: 25% Identity, 38% Similarity to CpaE [Caulobacter crescentus]. Alain Filloux, Centre National de la Recherche Scientifique, Marseille, France
Jul 16, 2006 PA4306 Pseudomonas aeruginosa PAO1 New gene name: flp. New product name: Type IVb pilin, Flp (previously hypothetical protein). New product name confidence: Class 1 (previously Class 4). New subcellular localization: Fimbrial. New subcellular localization confidence: Class 1 (localization experimentally demonstrated in P. aeruginosa). New PseudoCAP function class: Motility and attachment. New evidence reference: PMID: 16788194. New genomic context: This ORF is transcribed in a reverse orientation as compared to flp-tad-rcp gene cluster (PA4297-PA4305) responsible for its assembly. Alain Filloux, Centre National de la Recherche Scientifique, Marseille, France
Jul 16, 2006 PA4959 Pseudomonas aeruginosa PAO1 New gene name: fimX (previously blank). New product name: FimX (previously designated conserved hypothetical protein).New product name confidence: Class 1 (protein function experimentally demonstrated in P. aeruginosa). Removed alternate gene name: fimX. Removed alternate protein name: FimX. New structure feature: PF00990: GGDEF domain characteristic of diguanylate cyclases. New structure feature: PF00563: EAL domain (characteristic of phosphodiesterases). Remove structure feature: PF00563: Domain of unknown function 2. Remove structure feature: PF00990: Domain of unknown function (weak and partial). New evidence reference: PMID: 16677312. New comment: FimX exhibits phosphodiesterase, but not diguanylate cyclase, activity in vitro. Literature review. Approved by reference author Barbara Kazmierczak, Yale University, USA
Jul 16, 2006 PA4301 Pseudomonas aeruginosa PAO1 New gene name: tadB (previously blank). New product name: TadB (previously hypothetical protein). New product name confidence: Class 2 (previously Class 4). New evidence reference (PMID): 16788194. New evidence reference (PMID): 15837433. New PseudoCAP function class: Motility and attachment. New genomic context: Part of flp-tad-rcp gene cluster (PA4297-PA4305) required for assembly of Type IVb pilin, Flp. New homology: 23% Identity, 46% similarity to TadC [Actinobacillus actinomycetemcomitans]. New structure feature: Belongs to the GspF family of proteins Alain Filloux, Centre National de la Recherche Scientifique, Marseille, France
Jul 16, 2006 PA4302 Pseudomonas aeruginosa PAO1 New gene name: tadA (previously blank). New product name: TadA ATPase (previously designated probable type II secretion system protein). New product name confidence: Class 2 (previously Class 3). New evidence reference (PMID): 16788194. New evidence reference (PMID): 15837433. New PseudoCAP function class: Motility and attachment. New genomic context: Part of flp-tad-rcp gene cluster (PA4297-PA4305) required for assembly of Type IVb pilin, Flp. New homology: 44% Identity, 66% Similarity to TadA [Actinobacillus actinomycetemcomitans]. New structure feature: Belongs to the GspE family of traffic ATPases Alain Filloux, Centre National de la Recherche Scientifique, Marseille, France
Jul 16, 2006 PA4300 Pseudomonas aeruginosa PAO1 New gene name: tadC (previously blank). New product name: TadC (previously hypothetical protein). New product name confidence: Class 2 (previously Class 4). New evidence reference (PMID): 16788194. New evidence reference (PMID): 15837433. New PseudoCAP function class: Motility and attachment. New genomic context: Part of flp-tad-rcp gene cluster (PA4297-PA4305) required for assembly of Type IVb pilin, Flp. New homology: 21% Identity, 48% similarity to TadC [Actinobacillus actinomycetemcomitans]. New structure feature: Belongs to the GspF family of proteins Alain Filloux, Centre National de la Recherche Scientifique, Marseille, France
Jul 16, 2006 PA4304 Pseudomonas aeruginosa PAO1 New gene name: rcpA (previously blank). New product name: RcpA (previously probable type II secretion system protein). New product name confidence: Class 2 (previously Class 3). New evidence reference (PMID): 16788194. New evidence reference (PMID): 15837433. New PseudoCAP function class: Motility and attachment. New genomic context: Part of flp-tad-rcp gene cluster (PA4297-PA4305) required for assembly of Type IVb pilin, Flp. New homology: 33% Identity, 50% Similarity to RcpA [Actinobacillus actinomycetemcomitans]. New structure feature: Belongs to the GspA family of secretins. Alain Filloux, Centre National de la Recherche Scientifique, Marseille, France
Jul 16, 2006 PA4305 Pseudomonas aeruginosa PAO1 New gene name: rcpC (previously blank). New product name: RcpC (previously designated hypothetical protein). New product name confidence: Class 2 (previously Class 3). New evidence reference (PMID): 16788194. New evidence reference (PMID): 15837433. New PseudoCAP function class: Motility and attachment. New genomic context: Part of flp-tad-rcp gene cluster (PA4297-PA4305) required for assembly of Type IVb pilin, Flp. New homology: 26% Identity, 37% similarity to CpaB [Caulobacter crescentus CB15]. Alain Filloux, Centre National de la Recherche Scientifique, Marseille, France
Jul 16, 2006 PA4299 Pseudomonas aeruginosa PAO1 New gene name: tadD (previously blank). New product name: TadD (previously hypothetical protein). New product name confidence: Class 2 (previously Class 4). New evidence reference (PMID): 16788194. New evidence reference (PMID): 15837433. New PseudoCAP function class: Motility and attachment. New genomic context: Part of flp-tad-rcp gene cluster (PA4297-PA4305) required for assembly of Type IVb pilin, Flp. Alain Filloux, Centre National de la Recherche Scientifique, Marseille, France
41 annotation updates returned