Pseudomonas aeruginosa PAO1, PA4901 (mdlC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4901
Name
mdlC
Replicon chromosome
Genomic location 5498740 - 5500326 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs
Commenttranscription induced by vanillate

Cross-References

RefSeq NP_253588.1
GI 15600094
Affymetrix PA4901_mdlC_at
Entrez 882177
GenBank AAG08286.1
INSDC AAG08286.1
NCBI Locus Tag PA4901
protein_id(GenBank) gb|AAG08286.1|AE004903_4|gnl|PseudoCAP|PA4901
TIGR NTL03PA04902
UniParc UPI00000C5E6B
UniProtKB Acc Q9HUR2
UniProtKB ID MDLC_PSEAE
UniRef100 UniRef100_Q9HUR2
UniRef50 UniRef50_P20906
UniRef90 UniRef90_Q9HUR2

Product

Feature Type CDS
Coding Frame 1
Product Name
benzoylformate decarboxylase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -9.25
Kyte-Doolittle Hydrophobicity Value 0.144
Molecular Weight (kDa) 55.7
Isoelectric Point (pI) 5.60

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 591 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004523 (336 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4901
Search term: mdlC

Human Homologs

References

Mandelate pathway of Pseudomonas putida: sequence relationships involving mandelate racemase, (S)-mandelate dehydrogenase, and benzoylformate decarboxylase and expression of benzoylformate decarboxylase in Escherichia coli.
Tsou AY, Ransom SC, Gerlt JA, Buechter DD, Babbitt PC, Kenyon GL
Biochemistry 1990 Oct 23;29(42):9856-62
PubMed ID: 2271624