Pseudomonas aeruginosa SCV20265, SCV20265_5324
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa SCV20265
GCF_000510305.1|latest |
| Locus Tag |
SCV20265_5324
|
| Name |
|
| Replicon | chromosome |
| Genomic location | 5656539 - 5656784 (- strand) |
Cross-References
| RefSeq | YP_008984324.1 |
| GI | 568312055 |
| Entrez | 18075273 |
| NCBI Locus Tag | SCV20265_5324 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
HigA protein (antitoxin to HigB)
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -2.54 |
| Kyte-Doolittle Hydrophobicity Value | -0.159 |
| Molecular Weight (kDa) | 9000.1 |
| Isoelectric Point (pI) | 4.97 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 6JPI | ANTITOXIN/DNA | 03/27/19 | Crystal structure of PA4674 in complex with its operator DNA (28bp) from Pseudomonas aeruginosa | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); SYNTHETIC CONSTRUCT | 3.143 | X-RAY DIFFRACTION | 98.8 |
| 7CSV | ANTITOXIN | 08/17/20 | Pseudomonas aeruginosa antitoxin HigA | Pseudomonas aeruginosa PAO1 | 1.71 | X-RAY DIFFRACTION | 98.8 |
| 6LB3 | ANTITOXIN/DNA | 11/13/19 | Crystal structure of PA4674 in complex with its operator DNA (18bp) from Pseudomonas aeruginosa | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); SYNTHETIC CONSTRUCT | 2.497 | X-RAY DIFFRACTION | 98.8 |
| 7CSY | ANTITOXIN/DNA | 08/17/20 | Pseudomonas aeruginosa antitoxin HigA with higBA promoter | Pseudomonas aeruginosa PAO1; Pseudomonas aeruginosa UCBPP-PA14 | 2.29 | X-RAY DIFFRACTION | 98.8 |
| 7CSW | ANTITOXIN/DNA | 08/17/20 | Pseudomonas aeruginosa antitoxin HigA with pa2440 promoter | Pseudomonas aeruginosa PAO1; Pseudomonas aeruginosa UCBPP-PA14 | 1.97 | X-RAY DIFFRACTION | 98.8 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 170 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG004324 (343 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: SCV20265_5324
Search term: HigA protein (antitoxin to HigB)
|
Human Homologs
References
No references are associated with this feature.