Pseudomonas aeruginosa PACS2, A0K_RS13155

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0046677 response to antibiotic
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA2019
 ECO:0000249
sequence similarity evidence used in automatic assertion		 10952562
Molecular Function GO:0042910 xenobiotic transmembrane transporter activity
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA2019
 ECO:0000249
sequence similarity evidence used in automatic assertion		 10543738
Biological Process GO:0055085 transmembrane transport
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00529
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0022857 transmembrane transporter activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01730
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01730
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Antibiotic resistance and susceptibility Other PACS2 genes in this class
Transport of small molecules Other PACS2 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF111369 HlyD-like secretion proteins - - 53 300 4.71E-72
MobiDBLite mobidb-lite consensus disorder prediction - - 377 396 -
Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain 62 294 1.4E-10
NCBIfam TIGR01730 JCVI: efflux RND transporter periplasmic adaptor subunit IPR006143 RND efflux pump, membrane fusion protein 42 375 3.7E-71
Gene3D G3DSA:2.40.30.170 - - - 58 285 1.8E-68
Pfam PF00529 Cation efflux system protein CusB domain 1 IPR043602 Cation efflux system protein CusB, domain 1 40 360 5.0E-12
Coils Coil Coil - - 143 170 -
Gene3D G3DSA:2.40.50.100 - - - 64 208 1.8E-68
Gene3D G3DSA:1.10.287.470 Helix hairpin bin - - 99 172 1.8E-68
PANTHER PTHR30158 ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER - - 2 387 6.1E-118
Gene3D G3DSA:2.40.420.20 - - - 286 376 3.3E-16

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.