Pseudomonas sp. MRSN12121, TO66_RS29460

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02895
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02895
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006935 chemotaxis
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF50341
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF50341
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004673 protein histidine kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02895
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00088
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG psem02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psem02025 Biofilm formation - Pseudomonas aeruginosa 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 768 871 0.01
Coils Coil Coil - - 1156 1176 -
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 631 754 4.97E-26
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 909 1031 2.24E-13
Coils Coil Coil - - 1467 1490 -
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1217 1317 9.0E-14
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 1651 1669 2.4E-9
Coils Coil Coil - - 728 748 -
Coils Coil Coil - - 66 87 -
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1215 1335 3.53E-27
Gene3D G3DSA:3.40.50.2300 - - - 1856 1975 3.7E-43
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 631 735 7.1E-9
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 14 128 2.7E-12
SMART SM01231 H_kinase_dim_2 IPR004105 Histidine kinase CheA-like, homodimeric domain 1366 1505 6.3E-12
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 1856 1967 1.7E-28
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 1504 1690 3.5E-51
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1073 1164 4.1289E-11
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 633 719 2.0E-12
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 432 556 2.77E-13
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 6 103 0.29
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 1853 1972 1.99E-38
CDD cd17546 REC_hyHK_CKI1_RcsC-like - - 1856 1967 1.0075E-33
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 909 1036 9.1E-12
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 1550 1691 1.1E-22
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1215 1313 9.35451E-14
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 1854 1967 1.4E-38
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 631 727 2.81285E-9
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1073 1192 1.44E-25
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 768 859 2.38316E-9
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1075 1175 2.5E-13
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 631 762 1.0E-26
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1215 1344 1.6E-30
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1073 1170 1.9E-5
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 768 888 5.89E-20
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 1507 1688 4.19E-36
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 770 856 2.1E-11
PANTHER PTHR43395 SENSOR HISTIDINE KINASE CHEA - - 632 754 0.0
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 763 893 1.1E-17
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 1554 1690 1.8E-14
Pfam PF02895 Signal transducing histidine kinase, homodimeric domain IPR004105 Histidine kinase CheA-like, homodimeric domain 1368 1504 3.3E-5
Coils Coil Coil - - 1397 1424 -
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1067 1197 1.1E-26
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1215 1312 1.5E-8
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 10 101 4.4E-8
SMART SM00260 chew_2 IPR002545 CheW-like domain 1683 1827 4.5E-29
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 1595 1609 2.4E-9
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 7 130 4.06E-22
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 1675 1688 2.4E-9
FunFam G3DSA:3.30.565.10:FF:000016 Chemotaxis protein CheA, putative - - 1506 1690 1.1E-60
Pfam PF01584 CheW-like domain IPR002545 CheW-like domain 1696 1829 2.7E-23
Gene3D G3DSA:2.30.30.40 SH3 Domains - - 1765 1825 8.9E-20
SUPERFAMILY SSF50341 CheW-like IPR036061 CheW-like domain superfamily 1690 1823 2.22E-24
Gene3D G3DSA:1.10.287.560 - IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily 1367 1432 6.4E-5

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.