Pseudomonas sp. HMP271, DP64_RS14395

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03120
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03120
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003911 DNA ligase (NAD+) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00532
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00278
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PIRSF PIRSF001604 LigA IPR001679 NAD-dependent DNA ligase 1 623 0.0
FunFam G3DSA:1.10.150.20:FF:000007 DNA ligase - - 452 527 5.5E-29
SUPERFAMILY SSF56091 DNA ligase/mRNA capping enzyme, catalytic domain - - 5 326 6.3E-120
Gene3D G3DSA:1.10.287.610 Helix hairpin bin - - 2 68 1.5E-29
Coils Coil Coil - - 4 24 -
CDD cd00114 LIGANc IPR013839 NAD-dependent DNA ligase, adenylation 9 327 0.0
PIRSF PIRSF001604 LigA IPR001679 NAD-dependent DNA ligase 614 788 9.4E-33
Gene3D G3DSA:1.10.150.20 - - - 620 696 8.5E-12
Gene3D G3DSA:1.10.150.20 - - - 527 607 6.9E-24
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 414 605 1.04E-51
Gene3D G3DSA:3.30.470.30 DNA ligase/mRNA capping enzyme - - 69 325 1.6E-100
NCBIfam TIGR00575 JCVI: DNA ligase (NAD(+)) LigA IPR001679 NAD-dependent DNA ligase 14 607 0.0
Hamap MF_01588 DNA ligase [ligA]. IPR001679 NAD-dependent DNA ligase 5 783 53.103821
Pfam PF00533 BRCA1 C Terminus (BRCT) domain IPR001357 BRCT domain 709 781 2.4E-10
Pfam PF12826 Helix-hairpin-helix motif IPR041663 DisA/LigA, helix-hairpin-helix motif 628 684 1.6E-9
Gene3D G3DSA:1.10.150.20 - - - 452 526 1.0E-26
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 502 521 2100.0
Pfam PF12826 Helix-hairpin-helix motif IPR041663 DisA/LigA, helix-hairpin-helix motif 532 595 1.0E-19
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 327 400 9.3E-33
CDD cd17748 BRCT_DNA_ligase_like - - 712 781 1.98974E-27
Pfam PF03120 NAD-dependent DNA ligase OB-fold domain IPR004150 NAD-dependent DNA ligase, OB-fold 332 407 1.9E-34
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 617 701 1.93E-13
FunFam G3DSA:3.30.470.30:FF:000001 DNA ligase - - 68 325 3.7E-108
Pfam PF01653 NAD-dependent DNA ligase adenylation domain IPR013839 NAD-dependent DNA ligase, adenylation 7 328 3.2E-127
PANTHER PTHR23389 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 - - 16 764 7.8E-51
SMART SM00532 ligaN3 IPR013840 NAD-dependent DNA ligase, N-terminal 6 470 0.0
FunFam G3DSA:1.10.150.20:FF:000006 DNA ligase - - 528 605 3.4E-24
Gene3D G3DSA:6.20.10.30 - - - 401 451 1.9E-11
SMART SM00292 BRCT_7 IPR001357 BRCT domain 709 786 4.9E-9
SUPERFAMILY SSF52113 BRCT domain IPR036420 BRCT domain superfamily 711 783 2.62E-17
FunFam G3DSA:2.40.50.140:FF:000012 DNA ligase - - 327 400 2.0E-34
FunFam G3DSA:1.10.287.610:FF:000002 DNA ligase - - 2 67 1.2E-29
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 328 410 7.54E-28
Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type 417 456 3.3E-11
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 468 487 37.0
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 534 553 110.0
Gene3D G3DSA:3.40.50.10190 BRCT domain IPR036420 BRCT domain superfamily 697 784 5.4E-25
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 657 676 230.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.