Pseudomonas aeruginosa LESB58, PALES_02611 (gabD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.309.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009450 gamma-aminobutyric acid catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01780
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF53720
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0009013 succinate-semialdehyde dehydrogenase [NAD(P)+] activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01780
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other LESB58 genes in this class
Carbon compound catabolism Other LESB58 genes in this class
Central intermediary metabolism Other LESB58 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Glutamate metabolism ECO:0000037
not_recorded
PseudoCAP Butanoate metabolism ECO:0000037
not_recorded
PseudoCAP Tyrosine metabolism ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:3.40.309.10:FF:000004 Succinate-semialdehyde dehydrogenase I - - 258 447 1.8E-92
Gene3D G3DSA:3.40.309.10 Aldehyde Dehydrogenase; Chain A, domain 2 IPR016163 Aldehyde dehydrogenase, C-terminal 258 447 0.0
PANTHER PTHR43353 SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL - - 4 482 0.0
CDD cd07103 ALDH_F5_SSADH_GabD - - 30 480 0.0
Gene3D G3DSA:3.40.605.10 Aldehyde Dehydrogenase; Chain A, domain 1 IPR016162 Aldehyde dehydrogenase, N-terminal 25 472 0.0
Pfam PF00171 Aldehyde dehydrogenase family IPR015590 Aldehyde dehydrogenase domain 19 477 0.0
SUPERFAMILY SSF53720 ALDH-like IPR016161 Aldehyde/histidinol dehydrogenase 7 481 0.0
FunFam G3DSA:3.40.605.10:FF:000005 Succinate-semialdehyde dehydrogenase I - - 25 276 5.3E-124
NCBIfam TIGR01780 JCVI: succinate-semialdehyde dehydrogenase IPR010102 Succinate semialdehyde dehydrogenase 30 476 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.