Pseudomonas sp. UW4, PputUW4_04133 (nrdA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00317
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00317
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00317
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG ppuu01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG ppuu00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG ppuu00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
MobiDBLite mobidb-lite consensus disorder prediction - - 1 25 -
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 684 707 7.7E-47
Gene3D G3DSA:3.20.70.20 - - - 219 915 0.0
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 445 464 7.7E-47
NCBIfam TIGR02506 JCVI: ribonucleoside-diphosphate reductase subunit alpha IPR013346 Ribonucleotide reductase, class I, alpha subunit, C-terminal 296 907 0.0
FunFam G3DSA:3.20.70.20:FF:000009 Ribonucleoside-diphosphate reductase - - 218 915 0.0
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 618 641 7.7E-47
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 760 787 7.7E-47
SUPERFAMILY SSF51998 PFL-like glycyl radical enzymes - - 369 907 0.0
CDD cd01679 RNR_I - - 318 907 0.0
Pfam PF02867 Ribonucleotide reductase, barrel domain IPR000788 Ribonucleotide reductase large subunit, C-terminal 370 906 0.0
PANTHER PTHR11573 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN IPR039718 Ribonucleoside-diphosphate reductase large subunit 149 963 0.0
SUPERFAMILY SSF48168 R1 subunit of ribonucleotide reductase, N-terminal domain IPR008926 Ribonucleotide reductase R1 subunit, N-terminal 153 368 1.96E-63
Pfam PF03477 ATP cone domain IPR005144 ATP-cone domain 148 232 2.7E-6
Pfam PF03477 ATP cone domain IPR005144 ATP-cone domain 33 129 1.5E-18
Pfam PF00317 Ribonucleotide reductase, all-alpha domain IPR013509 Ribonucleotide reductase large subunit, N-terminal 293 364 2.8E-22
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 581 592 7.7E-47
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 656 678 7.7E-47

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.