Pseudomonas fulva 12-X, Psefu_2282

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009086 methionine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000381
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0046872 metal ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF52242
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008270 zinc ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000381
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008705 methionine synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000381
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0031419 cobalamin binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF52242
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0044237 cellular metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF51717
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0042558 pteridine-containing compound metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00809
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pfv01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pfv01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pfv00450 Selenocompound metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc folate transformations II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc folate transformations I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pfv00670 One carbon pool by folate 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pfv00270 Cysteine and methionine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pfv01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc L-methionine biosynthesis IV (archaea) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF52242 Cobalamin (vitamin B12)-binding domain IPR036724 Cobalamin-binding domain superfamily 746 896 3.01E-44
Gene3D G3DSA:3.20.20.330 - IPR036589 Homocysteine-binding domain superfamily 7 343 5.8E-124
SUPERFAMILY SSF51717 Dihydropteroate synthetase-like IPR011005 Dihydropteroate synthase-like 361 634 1.83E-89
SUPERFAMILY SSF56507 Methionine synthase activation domain-like IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily 907 1237 6.54E-125
Pfam PF02607 B12 binding domain IPR003759 Cobalamin (vitamin B12)-binding module, cap domain 662 735 3.4E-24
Gene3D G3DSA:3.10.196.10 - IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily 910 1236 0.0
NCBIfam TIGR02082 JCVI: methionine synthase IPR011822 Cobalamin-dependent methionine synthase 17 1204 0.0
Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain IPR004223 Vitamin B12-dependent methionine synthase, activation domain 943 1219 1.6E-121
FunFam G3DSA:1.10.1240.10:FF:000001 Methionine synthase - - 649 743 1.6E-44
SUPERFAMILY SSF82282 Homocysteine S-methyltransferase IPR036589 Homocysteine-binding domain superfamily 13 404 2.22E-117
CDD cd02069 methionine_synthase_B12_BD IPR033706 Methionine synthase, B12-binding domain 662 876 2.07032E-125
Gene3D G3DSA:1.10.288.10 - - - 942 1099 0.0
PANTHER PTHR45833 METHIONINE SYNTHASE - - 11 1236 0.0
SUPERFAMILY SSF47644 Methionine synthase domain IPR036594 Methionine synthase domain 655 742 9.81E-28
SMART SM01018 B12_binding_2_2 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain 660 743 3.1E-42
Gene3D G3DSA:3.20.20.20 - IPR011005 Dihydropteroate synthase-like 351 648 0.0
FunFam G3DSA:3.20.20.20:FF:000002 Methionine synthase - - 351 647 0.0
CDD cd00740 MeTr - - 361 617 9.15931E-125
Pfam PF02574 Homocysteine S-methyltransferase IPR003726 Homocysteine-binding domain 22 330 6.5E-79
Pfam PF00809 Pterin binding enzyme IPR000489 Pterin-binding domain 365 603 2.0E-58
FunFam G3DSA:3.20.20.330:FF:000001 Methionine synthase - - 7 343 0.0
FunFam G3DSA:3.40.50.280:FF:000001 Methionine synthase - - 748 900 1.1E-77
Gene3D G3DSA:1.10.1240.10 Methionine synthase domain IPR036594 Methionine synthase domain 649 743 3.0E-38
Gene3D G3DSA:3.40.50.280 - - - 748 900 4.0E-58
PIRSF PIRSF000381 Met_synth_MetH IPR011822 Cobalamin-dependent methionine synthase 6 1207 0.0
Pfam PF02310 B12 binding domain IPR006158 Cobalamin (vitamin B12)-binding domain 752 845 1.5E-18

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.