Pseudomonas syringae pv. tomato DC3000, PSPTO_3656 (ligA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003911 DNA ligase (NAD+) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03119
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03119
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03119
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00278
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pst03410 Base excision repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pst03420 Nucleotide excision repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pst03430 Mismatch repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pst03030 DNA replication 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:1.10.150.20 - - - 524 605 1.9E-22
FunFam G3DSA:2.40.50.140:FF:000012 DNA ligase - - 324 397 2.0E-34
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 612 696 7.31E-13
Pfam PF01653 NAD-dependent DNA ligase adenylation domain IPR013839 NAD-dependent DNA ligase, adenylation 4 324 1.5E-127
SUPERFAMILY SSF52113 BRCT domain IPR036420 BRCT domain superfamily 705 778 4.3E-16
Gene3D G3DSA:1.10.287.610 Helix hairpin bin - - 1 64 5.4E-28
Gene3D G3DSA:1.10.150.20 - - - 618 692 3.7E-10
Gene3D G3DSA:1.10.150.20 - - - 449 523 9.4E-27
Coils Coil Coil - - 1 21 -
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 324 397 5.6E-32
Gene3D G3DSA:6.20.10.30 - - - 398 448 4.9E-12
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 411 596 5.56E-49
PIRSF PIRSF001604 LigA IPR001679 NAD-dependent DNA ligase 611 784 1.3E-30
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 465 484 1.8
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 499 518 950.0
Hamap MF_01588 DNA ligase [ligA]. IPR001679 NAD-dependent DNA ligase 2 779 51.200619
PIRSF PIRSF001604 LigA IPR001679 NAD-dependent DNA ligase 1 622 0.0
SMART SM00292 BRCT_7 IPR001357 BRCT domain 705 782 1.8E-6
Pfam PF12826 Helix-hairpin-helix motif IPR041663 DisA/LigA, helix-hairpin-helix motif 626 680 1.7E-7
SUPERFAMILY SSF56091 DNA ligase/mRNA capping enzyme, catalytic domain - - 3 323 2.52E-117
FunFam G3DSA:1.10.287.610:FF:000002 DNA ligase - - 1 64 2.3E-28
Gene3D G3DSA:3.40.50.10190 BRCT domain IPR036420 BRCT domain superfamily 693 781 1.2E-22
FunFam G3DSA:1.10.150.20:FF:000007 DNA ligase - - 449 524 1.8E-28
Pfam PF14520 Helix-hairpin-helix domain - - 465 518 0.0055
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 531 550 140.0
Pfam PF03120 NAD-dependent DNA ligase OB-fold domain IPR004150 NAD-dependent DNA ligase, OB-fold 329 405 5.3E-34
FunFam G3DSA:1.10.150.20:FF:000006 DNA ligase - - 525 602 8.1E-23
NCBIfam TIGR00575 JCVI: DNA ligase (NAD(+)) LigA IPR001679 NAD-dependent DNA ligase 11 605 0.0
Gene3D G3DSA:3.30.470.30 DNA ligase/mRNA capping enzyme - - 65 322 6.4E-99
PANTHER PTHR23389 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 - - 17 764 8.3E-47
FunFam G3DSA:3.30.470.30:FF:000001 DNA ligase - - 65 322 5.5E-106
SMART SM00532 ligaN3 IPR013840 NAD-dependent DNA ligase, N-terminal 3 467 0.0
Pfam PF00533 BRCA1 C Terminus (BRCT) domain IPR001357 BRCT domain 705 777 1.0E-9
CDD cd17748 BRCT_DNA_ligase_like - - 708 777 1.7773E-22
Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type 415 453 1.1E-10
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 326 406 2.4E-27
Pfam PF12826 Helix-hairpin-helix motif IPR041663 DisA/LigA, helix-hairpin-helix motif 529 592 4.2E-20
CDD cd00114 LIGANc IPR013839 NAD-dependent DNA ligase, adenylation 6 324 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.