Pseudomonas aeruginosa UCBPP-PA14, PA14_49460 (nrdA)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Cellular Component	GO:0005971	ribonucleoside-diphosphate reductase complex	ISS Inferred from Sequence or Structural Similarity Term mapped from: PseudoCAP:PA1156	ECO:0000249 sequence similarity evidence used in automatic assertion	16829681
Molecular Function	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00317	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0005524	ATP binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00317	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006260	DNA replication	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00317	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Nucleotide biosynthesis and metabolism Other UCBPP-PA14 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pau00230	Purine metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pau01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Purine metabolism; Pyrimidine metabolism		ECO:0000037 not_recorded
KEGG	pau00240	Pyrimidine metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
CDD	cd01679	RNR_I	-	-	319	907	0.0
PRINTS	PR01183	Ribonucleotide reductase large chain signature	IPR000788	Ribonucleotide reductase large subunit, C-terminal	581	592	4.3E-48
SUPERFAMILY	SSF51998	PFL-like glycyl radical enzymes	-	-	370	907	0.0
FunFam	G3DSA:3.20.70.20:FF:000009	Ribonucleoside-diphosphate reductase	-	-	219	915	0.0
Pfam	PF03477	ATP cone domain	IPR005144	ATP-cone domain	149	233	8.3E-8
PRINTS	PR01183	Ribonucleotide reductase large chain signature	IPR000788	Ribonucleotide reductase large subunit, C-terminal	618	641	4.3E-48
Pfam	PF03477	ATP cone domain	IPR005144	ATP-cone domain	33	128	2.8E-18
NCBIfam	TIGR02506	JCVI: ribonucleoside-diphosphate reductase subunit alpha	IPR013346	Ribonucleotide reductase, class I, alpha subunit, C-terminal	297	907	0.0
SUPERFAMILY	SSF48168	R1 subunit of ribonucleotide reductase, N-terminal domain	IPR008926	Ribonucleotide reductase R1 subunit, N-terminal	154	369	4.45E-64
PRINTS	PR01183	Ribonucleotide reductase large chain signature	IPR000788	Ribonucleotide reductase large subunit, C-terminal	684	707	4.3E-48
Gene3D	G3DSA:3.20.70.20	-	-	-	220	915	0.0
PRINTS	PR01183	Ribonucleotide reductase large chain signature	IPR000788	Ribonucleotide reductase large subunit, C-terminal	446	465	4.3E-48
PRINTS	PR01183	Ribonucleotide reductase large chain signature	IPR000788	Ribonucleotide reductase large subunit, C-terminal	656	678	4.3E-48
Pfam	PF00317	Ribonucleotide reductase, all-alpha domain	IPR013509	Ribonucleotide reductase large subunit, N-terminal	294	365	7.6E-22
PRINTS	PR01183	Ribonucleotide reductase large chain signature	IPR000788	Ribonucleotide reductase large subunit, C-terminal	760	787	4.3E-48
PANTHER	PTHR11573	RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN	IPR039718	Ribonucleoside-diphosphate reductase large subunit	150	963	0.0
MobiDBLite	mobidb-lite	consensus disorder prediction	-	-	1	23	-
Pfam	PF02867	Ribonucleotide reductase, barrel domain	IPR000788	Ribonucleotide reductase large subunit, C-terminal	371	906	0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.