Pseudomonas aeruginosa 3576, AJ63_04177 (prpB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0046421 methylisocitrate lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02317
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019629 propionate catabolic process, 2-methylcitrate cycle
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02317
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF51621
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.20.20.60 - IPR040442 Pyruvate kinase-like domain superfamily 2 297 6.1E-105
SUPERFAMILY SSF51621 Phosphoenolpyruvate/pyruvate domain IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily 8 292 2.02E-100
PANTHER PTHR42905 PHOSPHOENOLPYRUVATE CARBOXYLASE - - 4 287 1.3E-84
Coils Coil Coil - - 281 298 -
Pfam PF13714 Phosphoenolpyruvate phosphomutase - - 19 256 8.3E-46
CDD cd00377 ICL_PEPM IPR039556 ICL/PEPM domain 12 255 1.40963E-94
NCBIfam TIGR02317 JCVI: methylisocitrate lyase IPR012695 2-methylisocitrate lyase 9 293 0.0
FunFam G3DSA:3.20.20.60:FF:000009 2-methylisocitrate lyase - - 4 297 0.0
Hamap MF_01939 2-methylisocitrate lyase [prpB]. IPR012695 2-methylisocitrate lyase 4 295 51.604546

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.