Pseudomonas sp. FH4, H097_RS01665

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003911 DNA ligase (NAD+) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03119
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03119
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03119
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00278
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type 412 450 1.6E-10
Gene3D G3DSA:6.20.10.30 - - - 395 445 1.1E-12
Pfam PF12826 Helix-hairpin-helix motif IPR041663 DisA/LigA, helix-hairpin-helix motif 625 678 2.6E-6
FunFam G3DSA:1.10.287.610:FF:000002 DNA ligase - - 1 64 1.5E-28
Hamap MF_01588 DNA ligase [ligA]. IPR001679 NAD-dependent DNA ligase 2 778 51.285011
Gene3D G3DSA:1.10.150.20 - - - 521 596 1.2E-21
PANTHER PTHR23389 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 - - 17 759 1.1E-46
SMART SM00532 ligaN3 IPR013840 NAD-dependent DNA ligase, N-terminal 3 464 0.0
FunFam G3DSA:2.40.50.140:FF:000012 DNA ligase - - 321 394 1.1E-34
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 323 403 3.43E-28
CDD cd00114 LIGANc IPR013839 NAD-dependent DNA ligase, adenylation 6 321 0.0
SUPERFAMILY SSF56091 DNA ligase/mRNA capping enzyme, catalytic domain - - 3 320 4.48E-116
Gene3D G3DSA:3.30.470.30 DNA ligase/mRNA capping enzyme - - 65 319 2.0E-98
Pfam PF01653 NAD-dependent DNA ligase adenylation domain IPR013839 NAD-dependent DNA ligase, adenylation 4 321 2.4E-125
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 462 481 4.0
FunFam G3DSA:1.10.150.20:FF:000006 DNA ligase - - 521 596 6.2E-22
FunFam G3DSA:1.10.150.20:FF:000007 DNA ligase - - 446 520 5.8E-30
PIRSF PIRSF001604 LigA IPR001679 NAD-dependent DNA ligase 610 783 2.1E-28
Pfam PF14520 Helix-hairpin-helix domain - - 462 516 0.0057
NCBIfam TIGR00575 JCVI: DNA ligase (NAD(+)) LigA IPR001679 NAD-dependent DNA ligase 11 592 0.0
Gene3D G3DSA:1.10.150.20 - - - 446 520 8.4E-28
Gene3D G3DSA:3.40.50.10190 BRCT domain IPR036420 BRCT domain superfamily 687 780 3.3E-21
SMART SM00292 BRCT_7 IPR001357 BRCT domain 704 781 1.4E-5
Pfam PF12826 Helix-hairpin-helix motif IPR041663 DisA/LigA, helix-hairpin-helix motif 526 589 8.1E-20
Pfam PF00533 BRCA1 C Terminus (BRCT) domain IPR001357 BRCT domain 707 775 6.5E-8
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 496 515 1300.0
Gene3D G3DSA:1.10.150.20 - - - 620 675 1.4E-8
Gene3D G3DSA:1.10.287.610 Helix hairpin bin - - 1 64 7.5E-28
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 610 696 3.08E-12
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 408 593 4.45E-50
Pfam PF03120 NAD-dependent DNA ligase OB-fold domain IPR004150 NAD-dependent DNA ligase, OB-fold 326 402 7.2E-35
PIRSF PIRSF001604 LigA IPR001679 NAD-dependent DNA ligase 1 600 0.0
CDD cd17748 BRCT_DNA_ligase_like - - 708 774 8.21715E-23
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 321 394 6.6E-33
FunFam G3DSA:3.30.470.30:FF:000001 DNA ligase - - 65 319 1.4E-104
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 528 547 140.0
SUPERFAMILY SSF52113 BRCT domain IPR036420 BRCT domain superfamily 708 780 4.3E-16

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.