Pseudomonas aeruginosa MTB-1, U769_12000

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004451 isocitrate lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00463
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF51621
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019752 carboxylic acid metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00463
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG paem01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paem01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paem01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paem00630 Glyoxylate and dicarboxylate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paem01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00463 Isocitrate lyase family IPR006254 Isocitrate lyase 141 329 4.3E-20
PIRSF PIRSF001362 ICL IPR006254 Isocitrate lyase 350 470 9.1E-12
Gene3D G3DSA:3.20.20.60 - IPR040442 Pyruvate kinase-like domain superfamily 61 591 1.4E-128
SUPERFAMILY SSF51621 Phosphoenolpyruvate/pyruvate domain IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily 69 574 3.56E-124
PIRSF PIRSF001362 ICL IPR006254 Isocitrate lyase 61 338 8.9E-29
CDD cd00377 ICL_PEPM IPR039556 ICL/PEPM domain 123 446 9.12994E-35
Pfam PF00463 Isocitrate lyase family IPR006254 Isocitrate lyase 390 459 1.6E-9
Pfam PF00463 Isocitrate lyase family IPR006254 Isocitrate lyase 492 590 3.3E-13
PIRSF PIRSF001362 ICL IPR006254 Isocitrate lyase 472 591 7.0E-8
PANTHER PTHR21631 ISOCITRATE LYASE/MALATE SYNTHASE IPR006254 Isocitrate lyase 62 591 2.7E-130

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.