Pseudomonas aeruginosa PAO1, PA4403 (secA)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0015031	protein transport	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	2841285	Reviewed by curator
Biological Process	GO:0017038	protein import	ISM Inferred from Sequence Model Term mapped from: InterPro:PF07517	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006605	protein targeting	ISM Inferred from Sequence Model Term mapped from: InterPro:MF_01382	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006886	intracellular protein transport	ISM Inferred from Sequence Model Term mapped from: InterPro:MF_01382	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0005524	ATP binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PF07517	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Cellular Component	GO:0016020	membrane	ISM Inferred from Sequence Model Term mapped from: InterPro:PF07517	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Protein secretion/export apparatus Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae03070	Bacterial secretion system	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae02024	Quorum sensing	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae03060	Protein export	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Pfam	PF07517	SecA DEAD-like domain	IPR011115	SecA DEAD-like, N-terminal	6	402	0.0
CDD	cd18803	SF2_C_secA	IPR044722	SecA, C-terminal helicase domain	420	589	4.18421E-83
CDD	cd17928	DEXDc_SecA	-	-	42	414	0.0
SMART	SM00958	SecA_PP_bind_2	IPR011130	SecA, preprotein cross-linking domain	228	358	1.7E-74
SMART	SM00957	SecA_DEAD_2	IPR011115	SecA DEAD-like, N-terminal	6	402	0.0
Hamap	MF_01382	Protein translocase subunit SecA [secA].	IPR000185	Protein translocase subunit SecA	5	832	20.073292
FunFam	G3DSA:3.40.50.300:FF:000113	Preprotein translocase subunit SecA	-	-	417	620	4.5E-100
PRINTS	PR00906	SecA protein signature	IPR000185	Protein translocase subunit SecA	63	87	1.7E-70
Gene3D	G3DSA:1.10.3060.10	Helical scaffold and wing domains of SecA	-	-	621	833	2.0E-77
PRINTS	PR00906	SecA protein signature	IPR000185	Protein translocase subunit SecA	413	426	1.7E-70
FunFam	G3DSA:3.40.50.300:FF:000081	Preprotein translocase subunit SecA	-	-	21	246	4.2E-110
PRINTS	PR00906	SecA protein signature	IPR000185	Protein translocase subunit SecA	339	361	1.7E-70
Gene3D	G3DSA:3.90.1440.10	-	-	-	231	370	0.0
SUPERFAMILY	SSF52540	P-loop containing nucleoside triphosphate hydrolases	IPR027417	P-loop containing nucleoside triphosphate hydrolase	416	618	4.9E-60
Coils	Coil	Coil	-	-	840	860	-
PANTHER	PTHR30612	SECA INNER MEMBRANE COMPONENT OF SEC PROTEIN SECRETION SYSTEM	IPR000185	Protein translocase subunit SecA	5	871	0.0
SUPERFAMILY	SSF81886	Helical scaffold and wing domains of SecA	IPR036266	SecA, Wing/Scaffold superfamily	620	904	1.19E-81
Pfam	PF02810	SEC-C motif	IPR004027	SEC-C motif	896	913	2.2E-10
SUPERFAMILY	SSF81767	Pre-protein crosslinking domain of SecA	IPR036670	SecA, preprotein cross-linking domain superfamily	227	368	1.57E-40
FunFam	G3DSA:1.10.3060.10:FF:000001	Preprotein translocase subunit SecA	-	-	621	833	1.8E-107
FunFam	G3DSA:3.90.1440.10:FF:000001	Preprotein translocase subunit SecA	-	-	229	368	5.8E-54
PRINTS	PR00906	SecA protein signature	IPR000185	Protein translocase subunit SecA	170	190	1.7E-70
Pfam	PF01043	SecA preprotein cross-linking domain	IPR011130	SecA, preprotein cross-linking domain	232	358	2.6E-34
Gene3D	G3DSA:3.40.50.300	-	IPR027417	P-loop containing nucleoside triphosphate hydrolase	417	620	1.1E-91
Coils	Coil	Coil	-	-	469	489	-
PRINTS	PR00906	SecA protein signature	IPR000185	Protein translocase subunit SecA	101	115	1.7E-70
NCBIfam	TIGR00963	JCVI: preprotein translocase subunit SecA	IPR000185	Protein translocase subunit SecA	28	818	0.0
Pfam	PF07516	SecA Wing and Scaffold domain	IPR011116	SecA Wing/Scaffold	617	830	5.2E-67
Gene3D	G3DSA:3.40.50.300	-	IPR027417	P-loop containing nucleoside triphosphate hydrolase	23	416	0.0
PRINTS	PR00906	SecA protein signature	IPR000185	Protein translocase subunit SecA	376	393	1.7E-70
MobiDBLite	mobidb-lite	consensus disorder prediction	-	-	857	916	-
PRINTS	PR00906	SecA protein signature	IPR000185	Protein translocase subunit SecA	117	127	1.7E-70
SUPERFAMILY	SSF52540	P-loop containing nucleoside triphosphate hydrolases	IPR027417	P-loop containing nucleoside triphosphate hydrolase	5	415	3.27E-88

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.