Pseudomonas aeruginosa PAO1, PA4367 (bifA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0071111 cyclic-guanylate-specific phosphodiesterase activity
IMP
Inferred from Mutant Phenotype 		ECO:0000016
loss-of-function mutant phenotype evidence		 17586641 Reviewed by curator
Biological Process GO:0044010 single-species biofilm formation
IMP
Inferred from Mutant Phenotype 		ECO:0000016
loss-of-function mutant phenotype evidence		 17586641 Reviewed by curator
Biological Process GO:1900191 negative regulation of single-species biofilm formation
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 17586641 Reviewed by curator

Functional Classifications Manually Assigned by PseudoCAP

Cell wall / LPS / capsule Other PAO1 genes in this class
Motility & Attachment Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae02025 Biofilm formation - Pseudomonas aeruginosa 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.30.70.270 - IPR043128 Reverse transcriptase/Diguanylate cyclase domain 249 418 1.6E-46
FunFam G3DSA:3.20.20.450:FF:000001 Cyclic di-GMP phosphodiesterase yahA - - 422 677 1.5E-106
CDD cd01948 EAL IPR001633 EAL domain 428 667 6.57272E-117
Pfam PF00990 Diguanylate cyclase, GGDEF domain IPR000160 GGDEF domain 251 407 2.4E-37
SMART SM00052 duf2_2 IPR001633 EAL domain 421 667 2.8E-122
NCBIfam TIGR00254 JCVI: diguanylate cyclase (GGDEF) domain IPR000160 GGDEF domain 249 409 2.1E-28
Gene3D G3DSA:3.20.20.450 EAL domain IPR035919 EAL domain superfamily 422 685 1.5E-102
CDD cd01949 GGDEF IPR000160 GGDEF domain 251 409 3.42982E-42
Coils Coil Coil - - 415 435 -
Pfam PF00563 EAL domain IPR001633 EAL domain 427 662 4.9E-75
SUPERFAMILY SSF55073 Nucleotide cyclase IPR029787 Nucleotide cyclase 255 411 2.2E-38
PANTHER PTHR33121 CYCLIC DI-GMP PHOSPHODIESTERASE PDEF - - 213 681 0.0
SUPERFAMILY SSF141868 EAL domain-like IPR035919 EAL domain superfamily 426 676 4.71E-93
SMART SM00267 duf1_3 IPR000160 GGDEF domain 239 411 1.1E-43

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.