Pseudomonas aeruginosa PAO1, PA1798 (parS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0000155 phosphorelay sensor kinase activity
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 20547815 Reviewed by curator
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00388
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00304
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00388
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Antibiotic resistance and susceptibility Other PAO1 genes in this class
Two-component regulatory systems Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01503 Cationic antimicrobial peptide (CAMP) resistance 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01501 beta-Lactam resistance 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Two-component System ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR44936 SENSOR PROTEIN CREC - - 2 425 3.2E-68
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 371 381 2.5E-12
CDD cd06225 HAMP - - 154 202 1.24334E-9
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 388 406 2.5E-12
SUPERFAMILY SSF158472 HAMP domain-like - - 158 206 3.4E-6
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 277 426 2.4E-34
SMART SM00304 HAMP_11 IPR003660 HAMP domain 155 207 6.9E-9
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 353 367 2.5E-12
Gene3D G3DSA:1.10.287.130 - - - 201 269 1.5E-15
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 321 425 2.4E-21
Gene3D G3DSA:1.10.8.500 HAMP domain in histidine kinase - - 154 200 3.7E-5
CDD cd00082 HisKA IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 209 269 7.06336E-8
Pfam PF00672 HAMP domain IPR003660 HAMP domain 158 203 6.0E-9
SUPERFAMILY SSF47384 Homodimeric domain of signal transducing histidine kinase IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily 191 274 4.51E-15
SMART SM00388 HisKA_10 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 208 273 2.6E-11
Pfam PF00512 His Kinase A (phospho-acceptor) domain IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 209 273 6.5E-9
CDD cd16939 HATPase_RstB-like - - 323 426 4.23999E-59
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 318 428 7.0E-32
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 263 424 5.37E-39

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.