Pseudomonas thermotolerans J53, M905_RS0113500

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004451 isocitrate lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00463
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00377
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019752 carboxylic acid metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00463
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF51621 Phosphoenolpyruvate/pyruvate domain IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily 5 515 2.65E-124
PIRSF PIRSF001362 ICL IPR006254 Isocitrate lyase 295 411 1.0E-11
PANTHER PTHR21631 ISOCITRATE LYASE/MALATE SYNTHASE IPR006254 Isocitrate lyase 2 532 5.7E-126
Gene3D G3DSA:3.20.20.60 - IPR040442 Pyruvate kinase-like domain superfamily 2 532 1.6E-128
PIRSF PIRSF001362 ICL IPR006254 Isocitrate lyase 1 278 4.6E-29
Pfam PF00463 Isocitrate lyase family IPR006254 Isocitrate lyase 98 269 2.4E-21
Pfam PF00463 Isocitrate lyase family IPR006254 Isocitrate lyase 424 531 6.5E-14
CDD cd00377 ICL_PEPM IPR039556 ICL/PEPM domain 67 267 1.62275E-33
Pfam PF00463 Isocitrate lyase family IPR006254 Isocitrate lyase 341 391 8.5E-9
PIRSF PIRSF001362 ICL IPR006254 Isocitrate lyase 414 532 6.5E-8

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.