Pseudomonas aeruginosa PACS2, A0K_RS22835

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa PACS2
GCF_000168335.1|latest
Locus Tag
A0K_RS22835
Name
Replicon chromosome
Genomic location 4878189 - 4878947 (- strand)

Cross-References

RefSeq ZP_01367176.1
GI 107103258
NCBI Locus Tag A0K_RS22835

Product

Feature Type CDS
Coding Frame 1
Product Name
tRNA (guanine-N1)-methyltransferase
Synonyms
Evidence for Translation
Charge (pH 7) -9.61
Kyte-Doolittle Hydrophobicity Value -0.461
Molecular Weight (kDa) 28.4
Isoelectric Point (pI) 4.89

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6JKI TRANSFERASE 03/01/19 Crystal structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa Pseudomonas aeruginosa 2.59 X-RAY DIFFRACTION 99.6
5WYQ TRANSFERASE 01/15/17 Crystal Structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa Pseudomonas aeruginosa (strain UCBPP-PA14) 2.16 X-RAY DIFFRACTION 99.6
5WYR TRANSFERASE 01/15/17 Crystal structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa Pseudomonas aeruginosa (strain UCBPP-PA14) 2.45 X-RAY DIFFRACTION 99.6
5ZHM TRANSFERASE 03/13/18 Crystal structure of TrmD from Pseudomonas aeruginosa in complex with active-site inhibitor Pseudomonas aeruginosa 2.76 X-RAY DIFFRACTION 99.6
6AFK TRANSFERASE 08/08/18 Crystal structure of TrmD from Pseudomonas aeruginosa in complex with active-site inhibitor Pseudomonas aeruginosa UCBPP-PA14 2.75 X-RAY DIFFRACTION 99.6
5ZHN TRANSFERASE 03/13/18 Crystal structure of TrmD from Pseudomonas aeruginosa in complex with active-site inhibitor Pseudomonas aeruginosa UCBPP-PA14 2.65 X-RAY DIFFRACTION 99.6
6JOE TRANSFERASE 03/20/19 Crystal structure of TrmD from Pseudomonas aeruginosa in complex with active-site inhibitor Pseudomonas aeruginosa UCBPP-PA14 2.21 X-RAY DIFFRACTION 99.6

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001939 (537 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: A0K_RS22835

Human Homologs

References

No references are associated with this feature.