Pseudomonas putida KT2440, PP_4959 (cfcR)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas putida KT2440 (TIGR)
GCF_000007565.2|latest |
| Locus Tag |
PP_4959
|
| Name |
cfcR
Synonym: Rup4959 |
| Replicon | chromosome |
| Genomic location | 5649066 - 5651192 (- strand) |
Cross-References
| RefSeq | NP_747062.1 |
| GI | 26991637 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
CfcR
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | |
| Kyte-Doolittle Hydrophobicity Value | -0.077 |
| Molecular Weight (kDa) | 78.9 |
| Isoelectric Point (pI) | 5.07 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Pathogen Association Analysis
| Results | Analysis not done |
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group | |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PP_4959
Search term: cfcR
Search term: CfcR
|
Human Homologs
References
|
C-di-GMP and biofilm are regulated in Pseudomonas putida by the CfcA/CfcR two-component system in response to salts.
Tagua VG, Molina-Henares MA, Travieso ML, Nisa-Martínez R, Quesada JM, Espinosa-Urgel M, Ramos-González MI
Environ Microbiol 2022 Jan;24(1):158-178
PubMed ID: 35001503
|
|
Genetic Dissection of the Regulatory Network Associated with High c-di-GMP Levels in Pseudomonas putida KT2440.
Ramos-González MI, Travieso ML, Soriano MI, Matilla MA, Huertas-Rosales Ó, Barrientos-Moreno L, Tagua VG, Espinosa-Urgel M
Front Microbiol 2016;7:1093
PubMed ID: 27489550
|