Pseudomonas aeruginosa MH19, PAMH19_RS10840 (fabG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa MH19
GCF_001051345.1|latest
Locus Tag
PAMH19_RS10840
Name
fabG
Synonym: PAMH19_2102
Replicon contig MH19_contig6
Genomic location 164850 - 165593 (+ strand)

Cross-References

RefSeq WP_049250726.1
GI 896259430
EC Number 1.1.1.100

Product

Feature Type CDS
Coding Frame 1
Product Name
3-ketoacyl-ACP reductase
Synonyms
Evidence for Translation
Charge (pH 7) 0.48
Kyte-Doolittle Hydrophobicity Value 0.176
Molecular Weight (kDa) 25.6
Isoelectric Point (pI) 7.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4BO7 OXIDOREDUCTASE 05/18/13 Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with N-(2,3-dihydro-1H-inden- 5-yl)tetrazolo(1,5-b)pyridazin-6-amine at 2.6A resolution PSEUDOMONAS AERUGINOSA 2.6 X-RAY DIFFRACTION 99.6
4BNV OXIDOREDUCTASE 05/17/13 Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 1-(2-chlorophenyl)-3-(1- methylbenzimidazol-2-yl)urea at 2.5A resolution PSEUDOMONAS AERUGINOSA 2.5 X-RAY DIFFRACTION 99.6
4BNU OXIDOREDUCTASE 05/17/13 Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 2-phenyl-4-(1,2,4- triazol-4-yl)quinazoline at 2.0A resolution PSEUDOMONAS AERUGINOSA 2 X-RAY DIFFRACTION 99.6
4BO6 OXIDOREDUCTASE 05/18/13 Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 2,3-dihydroindol-1-yl-(2- thiophen-3-yl-1,3-thiazol-4-yl)methanone at 2.8A resolution PSEUDOMONAS AERUGINOSA 2.8 X-RAY DIFFRACTION 99.6
4BNW OXIDOREDUCTASE 05/17/13 Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with an unknown ligand at 1. 6A resolution PSEUDOMONAS AERUGINOSA 1.6 X-RAY DIFFRACTION 99.6
4BO8 OXIDOREDUCTASE 05/18/13 Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 1-(2-amino-4- phenylimidazol-1-yl)-3-(2-fluorophenyl)urea at 2.7A resolution PSEUDOMONAS AERUGINOSA 2.7 X-RAY DIFFRACTION 99.6
4AFN OXIDOREDUCTASE 01/20/12 Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa at 2.3A resolution PSEUDOMONAS AERUGINOSA 2.3 X-RAY DIFFRACTION 99.6
4AG3 OXIDOREDUCTASE 01/24/12 Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with NADPH at 1.8A resolution PSEUDOMONAS AERUGINOSA 1.8 X-RAY DIFFRACTION 99.6
4BNT OXIDOREDUCTASE 05/17/13 Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 2-(trifluoromethyl)-1H- benzimidazole at 2.3A resolution PSEUDOMONAS AERUGINOSA 2.3 X-RAY DIFFRACTION 99.6

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002615 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PAMH19_RS10840
Search term: fabG

Human Homologs

Ensembl 110, assembly GRCh38.p14
carbonyl reductase 4 [Source:HGNC Symbol;Acc:HGNC:25891]
E-value: 5.7e-41
Percent Identity: 42.7

References

No references are associated with this feature.