Pseudomonas aeruginosa LESB58, PALES_15351 (rhlR)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa LESB58
GCF_000026645.1|latest |
| Locus Tag |
PALES_15351
|
| Name |
rhlR
|
| Replicon | chromosome |
| Genomic location | 1667618 - 1668343 (+ strand) |
Cross-References
| RefSeq | YP_002439139 |
| GI | 218890275 |
| Entrez | 7180880 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
transcriptional regulator RhlR
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | 0.59 |
| Kyte-Doolittle Hydrophobicity Value | -0.278 |
| Molecular Weight (kDa) | 27.6 |
| Isoelectric Point (pI) | 7.19 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 7R3E | TRANSCRIPTION | 02/07/22 | Fusion construct of PqsE and RhlR in complex with the synthetic antagonist mBTL | Pseudomonas aeruginosa PAO1 | 3.46 | X-RAY DIFFRACTION | 100.0 |
| 7R3J | TRANSCRIPTION | 02/07/22 | Nativ complex of PqsE and RhlR with the synthetic antagonist mBTL | Pseudomonas aeruginosa PAO1 | 3.06 | X-RAY DIFFRACTION | 100.0 |
| 8B4A | SIGNALING PROTEIN | 09/20/22 | Nativ complex of PqsE and RhlR with autoinducer C4-HSL | Pseudomonas aeruginosa PAO1 | 3.06 | X-RAY DIFFRACTION | 100.0 |
| 8DQ0 | TRANSCRIPTION | 07/18/22 | Quorum-sensing receptor RhlR bound to PqsE | Pseudomonas aeruginosa | 3.74 | ELECTRON MICROSCOPY | 100.0 |
| 8DQ1 | TRANSCRIPTION/DNA | 07/18/22 | Quorum-sensing receptor RhlR bound to PqsE | Pseudomonas aeruginosa; SYNTHETIC CONSTRUCT | 4.1 | ELECTRON MICROSCOPY | 100.0 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 188 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG001096 (1439 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PALES_15351
Search term: rhlR
Search term: transcriptional regulator RhlR
|
Human Homologs
References
No references are associated with this feature.