Pseudomonas aeruginosa MRSN 317, T648_RS13755 (ligD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa MRSN 317
GCF_000982125.1|latest
Locus Tag
T648_RS13755
Name
ligD
Synonym: T648_13755
Replicon contig12
Genomic location 112257 - 114740 (+ strand)

Cross-References

RefSeq WP_003109866.1
GI 489200654
EC Number 6.5.1.1

Product

Feature Type CDS
Coding Frame 1
Product Name
ATP-dependent DNA ligase
Synonyms
Evidence for Translation
Charge (pH 7) 17.94
Kyte-Doolittle Hydrophobicity Value -0.520
Molecular Weight (kDa) 92.8
Isoelectric Point (pI) 9.59

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2FAO HYDROLASE/TRANSFERASE 12/07/05 Crystal Structure of Pseudomonas aeruginosa LigD polymerase domain Pseudomonas aeruginosa 1.5 X-RAY DIFFRACTION 99.7
3N9D LIGASE 05/28/10 Monoclinic Structure of P. aeruginosa LigD phosphoesterase domain Pseudomonas aeruginosa 2.3 X-RAY DIFFRACTION 98.8
2FAR Hydrolase/Transferase 12/07/05 Crystal Structure of Pseudomonas aeruginosa LigD polymerase domain with dATP and Manganese Pseudomonas aeruginosa 1.9 X-RAY DIFFRACTION 99.7
3N9B LIGASE 05/28/10 Crystal Structure of the P. aeruginosa LigD phosphoesterase domain Pseudomonas aeruginosa 1.92 X-RAY DIFFRACTION 98.8
2LJ6 DNA BINDING PROTEIN 09/06/11 Solution Structure and DNA-binding Properties of the Phosphoesterase Domain of DNA Ligase D Pseudomonas aeruginosa NOT SOLUTION NMR 98.9
2FAQ HYDROLASE/TRANSFERASE 12/07/05 Crystal Structure of Pseudomonas aeruginosa LigD polymerase domain with ATP and Manganese Pseudomonas aeruginosa 1.9 X-RAY DIFFRACTION 99.7

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003336 (490 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: T648_RS13755
Search term: ligD

Human Homologs

References

No references are associated with this feature.