Pseudomonas aeruginosa PSE305, TY30_RS03615

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa PSE305
GCF_000750905.1|latest
Locus Tag
TY30_RS03615
Name
Synonym: PSE305_07330c
Replicon chromosome
Genomic location 777052 - 779064 (- strand)

Cross-References

RefSeq WP_003145650.1
GI 489237386

Product

Feature Type CDS
Coding Frame 1
Product Name
flagellar biosynthesis protein FlgM
Synonyms
Evidence for Translation
Charge (pH 7) -5.76
Kyte-Doolittle Hydrophobicity Value -0.254
Molecular Weight (kDa) 73.3
Isoelectric Point (pI) 6.29

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2ZWS HYDROLASE 12/17/08 Crystal Structure Analysis of neutral ceramidase from Pseudomonas aeruginosa Pseudomonas aeruginosa 1.4 X-RAY DIFFRACTION 100.0
2ZXC HYDROLASE 12/22/08 Ceramidase complexed with C2 Pseudomonas aeruginosa 2.2 X-RAY DIFFRACTION 100.0

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name Source Accession Source DB Version Target Accession Target Description Percent Identity Alignment Length E-Value
N-[(1R,2R,3E)-2-hydroxy-1-(hydroxymethyl)heptadec-3-en-1-yl]acetamide DB06960 DrugBank 5.1.4 Q9I596 Neutral ceramidase 99.6 670 0.0e+00

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000812 (298 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: TY30_RS03615

Human Homologs

Ensembl 110, assembly GRCh38.p14
N-acylsphingosine amidohydrolase 2 [Source:HGNC Symbol;Acc:HGNC:18860]
E-value: 2.4e-118
Percent Identity: 36.2
Ensembl 110, assembly GRCh38.p14
N-acylsphingosine amidohydrolase 2 [Source:HGNC Symbol;Acc:HGNC:18860]
E-value: 2.4e-118
Percent Identity: 36.2

References

No references are associated with this feature.