Pseudomonas protegens CHA0, PFLCHA0_c33010 (acrD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas protegens CHA0 - Assembly GCF_000397205.1
GCF_000397205.1|latest
Locus Tag
PFLCHA0_c33010
Name
acrD
Replicon chromosome
Genomic location 3695414 - 3698512 (+ strand)

Cross-References

RefSeq YP_008000575.1
GI 501680749
Entrez 15561217
NCBI Locus Tag PFLCHA0_c33010

Product

Feature Type CDS
Coding Frame 1
Product Name
putative aminoglycoside efflux pump
Synonyms
Evidence for Translation
Charge (pH 7) -9.34
Kyte-Doolittle Hydrophobicity Value 0.360
Molecular Weight (kDa) 110260.6
Isoelectric Point (pI) 5.28

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
adeF AdeF is the membrane fusion protein of the multidrug efflux complex AdeFGH. [PMID:20696879] ARO:3000777 protein homolog model Strict 782.7 44.02 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 487 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000417 (2093 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PFLCHA0_c33010
Search term: acrD

Human Homologs

References

No references are associated with this feature.