Pseudomonas protegens Pf-5, PFL_5445 (lipA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas protegens Pf-5
GCF_000012265.1|latest
Locus Tag
PFL_5445
Name
lipA
Replicon chromosome
Genomic location 6216079 - 6217101 (- strand)

Cross-References

RefSeq YP_262513.1
GI 70732750
EC Number 2.8.1.8
Entrez 3479837
INSDC AAY94655.1
NCBI Locus Tag PFL_5445
UniParc UPI000054E018
UniProtKB Acc Q4K5H0
UniProtKB ID Q4K5H0_PSEF5
UniRef100 UniRef100_Q4K5H0
UniRef50 UniRef50_Q9JZA5
UniRef90 UniRef90_Q87VW7

Product

Feature Type CDS
Coding Frame 1
Product Name
lipoyl synthase
Synonyms
Evidence for Translation
Charge (pH 7) 4.20
Kyte-Doolittle Hydrophobicity Value -0.294
Molecular Weight (kDa) 38.1
Isoelectric Point (pI) 8.08

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 495 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001687 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PFL_5445
Search term: lipA
Search term: lipoyl synthase

Human Homologs

Ensembl 110, assembly GRCh38.p14
lipoic acid synthetase [Source:HGNC Symbol;Acc:HGNC:16429]
E-value: 1.4e-74
Percent Identity: 48.2

References

No references are associated with this feature.