Pseudomonas syringae pv. tomato DC3000, PSPTO_1499 (wspR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas syringae pv. tomato DC3000 (Buell et al., 2003)
GCF_000007805.1|latest
Locus Tag
PSPTO_1499
NCBI Old Locus TagPSPTO1499
Name
wspR
Synonym: PSPTO1499
Replicon chromosome
Genomic location 1655919 - 1656923 (+ strand)

Cross-References

RefSeq NP_791325.1
GI 28868706
Entrez 1183136
INSDC AAO55020.1
NCBI Locus Tag PSPTO_1499
NCBI Old Locus Tag PSPTO1499
UniParc UPI000000881D
UniProtKB Acc Q886S7
UniProtKB ID Q886S7_PSESM
UniRef100 UniRef100_Q886S7
UniRef50 UniRef50_Q886S7
UniRef90 UniRef90_Q886S7

Product

Feature Type CDS
Coding Frame 1
Product Name
diguanylate cyclase response regulator, WspR
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -5.13
Kyte-Doolittle Hydrophobicity Value -0.238
Molecular Weight (kDa) 36.9
Isoelectric Point (pI) 5.87

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3I5A SIGNALING PROTEIN 07/03/09 Crystal structure of full-length WpsR from Pseudomonas syringae Pseudomonas syringae pv. tomato 2.796 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 598 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000167 (2758 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPTO_1499
Search term: wspR

Human Homologs

References

Determinants for the activation and autoinhibition of the diguanylate cyclase response regulator WspR.
De N, Navarro MV, Raghavan RV, Sondermann H
J Mol Biol 2009 Oct 30;393(3):619-33
PubMed ID: 19695263