Pseudomonas aeruginosa PA7, PSPA7_3496 (clpP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_3496
Name
clpP
Replicon chromosome
Genomic location 3623840 - 3624481 (- strand)

Cross-References

RefSeq YP_001348854.1
GI 152986423
EC Number 3.4.21.92
Entrez 5359421
NCBI Locus Tag PSPA7_3496

Product

Feature Type CDS
Coding Frame 1
Product Name
ATP-dependent Clp protease proteolytic subunit
Synonyms
Evidence for Translation
Charge (pH 7) -2.42
Kyte-Doolittle Hydrophobicity Value -0.053
Molecular Weight (kDa) 23.5
Isoelectric Point (pI) 6.39

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7M1M HYDROLASE 03/13/21 Crystal structure of Pseudomonas aeruginosa ClpP1 Pseudomonas aeruginosa 2.6 X-RAY DIFFRACTION 99.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 582 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003596 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_3496
Search term: clpP

Human Homologs

Ensembl 110, assembly GRCh38.p14
caseinolytic mitochondrial matrix peptidase proteolytic subunit [Source:HGNC Symbol;Acc:HGNC:2084]
E-value: 3.6e-60
Percent Identity: 57.5

References

No references are associated with this feature.