Pseudomonas aeruginosa PA7, PSPA7_2578 (purB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_2578
Name
purB
Replicon chromosome
Genomic location 2600086 - 2601456 (- strand)

Cross-References

RefSeq YP_001347942.1
GI 152985465
EC Number 4.3.2.2
Entrez 5357185
INSDC ABR82648.1
NCBI Locus Tag PSPA7_2578
UniParc UPI0000D736A7
UniProtKB Acc A6V4F7
UniProtKB ID A6V4F7_PSEA7
UniRef100 UniRef100_A6V4F7
UniRef50 UniRef50_Q9I0K9
UniRef90 UniRef90_Q9I0K9

Product

Feature Type CDS
Coding Frame 1
Product Name
adenylosuccinate lyase
Synonyms
Evidence for Translation
Charge (pH 7) -7.39
Kyte-Doolittle Hydrophobicity Value -0.121
Molecular Weight (kDa) 50.5
Isoelectric Point (pI) 5.83

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7T29 LYASE 12/03/21 Crystal Structure of Adenylosuccinate lyase (ASL) from Pseudomonas aeruginosa complexed with AMP Pseudomonas aeruginosa 1.5 X-RAY DIFFRACTION 98.9
7T24 LYASE 12/03/21 Crystal Structure of Adenylosuccinate lyase (ASL) from Pseudomonas aeruginosa Pseudomonas aeruginosa 1.45 X-RAY DIFFRACTION 98.9

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 605 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002924 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_2578
Search term: purB

Human Homologs

References

No references are associated with this feature.