Pseudomonas aeruginosa PA7, PSPA7_2578 (purB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006188 IMP biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF08328
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009152 purine ribonucleotide biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00928
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004018 N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00928
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF48557
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PA7 genes in this class
Nucleotide biosynthesis and metabolism Other PA7 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pap00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc inosine-5'-phosphate biosynthesis III InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc inosine-5'-phosphate biosynthesis II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc inosine-5'-phosphate biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pap01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap00250 Alanine, aspartate and glutamate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc adenosine ribonucleotides <i>de novo</i> biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:1.10.275.10:FF:000003 Adenylosuccinate lyase - - 1 117 2.3E-55
Gene3D G3DSA:1.10.275.10 - IPR024083 Fumarase/histidase, N-terminal 1 117 1.6E-48
PANTHER PTHR43411 ADENYLOSUCCINATE LYASE IPR047136 Adenylosuccinate lyase PurB, bacteria 2 456 0.0
SUPERFAMILY SSF48557 L-aspartase-like IPR008948 L-Aspartase-like 10 455 2.36E-105
NCBIfam TIGR00928 JCVI: adenylosuccinate lyase IPR004769 Adenylosuccinate lyase 12 455 0.0
Pfam PF00206 Lyase IPR022761 Fumarate lyase, N-terminal 14 313 7.0E-67
CDD cd01598 PurB - - 23 447 0.0
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 117 135 1.2E-18
FunFam G3DSA:1.20.200.10:FF:000004 Adenylosuccinate lyase - - 118 385 0.0
Gene3D G3DSA:1.20.200.10 Fumarase/aspartase (Central domain) - - 118 450 0.0
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 163 181 1.2E-18
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 252 279 1.2E-18
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 295 311 1.2E-18
Pfam PF08328 Adenylosuccinate lyase C-terminal IPR013539 Adenylosuccinate lyase PurB, C-terminal 332 446 1.0E-50
FunFam G3DSA:1.10.40.30:FF:000004 Adenylosuccinate lyase - - 383 446 1.6E-33
Gene3D G3DSA:1.10.40.30 - - - 383 446 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.