Pseudomonas aeruginosa PA7, PSPA7_1649 (rhlR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_1649
Name
rhlR
Replicon chromosome
Genomic location 1688253 - 1688927 (+ strand)

Cross-References

RefSeq YP_001347033.1
GI 152989609
Entrez 5357611
INSDC ABR86792.1
NCBI Locus Tag PSPA7_1649
UniParc UPI00003960C6
UniProtKB Acc A6V1U8
UniProtKB ID A6V1U8_PSEA7
UniRef100 UniRef100_P54292
UniRef50 UniRef50_P54292
UniRef90 UniRef90_P54292

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator RhlR
Synonyms
Evidence for Translation
Charge (pH 7) 1.59
Kyte-Doolittle Hydrophobicity Value -0.251
Molecular Weight (kDa) 25.5
Isoelectric Point (pI) 7.63

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
8DQ1 TRANSCRIPTION/DNA 07/18/22 Quorum-sensing receptor RhlR bound to PqsE Pseudomonas aeruginosa; SYNTHETIC CONSTRUCT 4.1 ELECTRON MICROSCOPY 100.0
7R3J TRANSCRIPTION 02/07/22 Nativ complex of PqsE and RhlR with the synthetic antagonist mBTL Pseudomonas aeruginosa PAO1 3.06 X-RAY DIFFRACTION 100.0
7R3E TRANSCRIPTION 02/07/22 Fusion construct of PqsE and RhlR in complex with the synthetic antagonist mBTL Pseudomonas aeruginosa PAO1 3.46 X-RAY DIFFRACTION 100.0
8DQ0 TRANSCRIPTION 07/18/22 Quorum-sensing receptor RhlR bound to PqsE Pseudomonas aeruginosa 3.74 ELECTRON MICROSCOPY 100.0
8B4A SIGNALING PROTEIN 09/20/22 Nativ complex of PqsE and RhlR with autoinducer C4-HSL Pseudomonas aeruginosa PAO1 3.06 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 191 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001096 (1439 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_1649
Search term: rhlR

Human Homologs

References

No references are associated with this feature.