Pseudomonas chlororaphis EA105, NZ35_RS17920 (ampC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas chlororaphis EA105
GCF_000783395.1|latest
Locus Tag
NZ35_RS17920
NCBI Old Locus TagNZ35_17940
Name
ampC
Synonym: NZ35_17940
Replicon contig_17
Genomic location 16152 - 17318 (- strand)

Cross-References

RefSeq WP_038364602.1
GI 740578819
EC Number 3.5.2.6
INSDC KHA71961.1
NCBI Locus Tag NZ35_RS17920
NCBI Old Locus Tag NZ35_17940
UniParc UPI0005370001
UniProtKB Acc A0A0A6FGT3
UniProtKB ID A0A0A6FGT3_9PSED
UniRef100 UniRef100_A0A0A6FGT3
UniRef50 UniRef50_P85302
UniRef90 UniRef90_A0A0A6FGT3

Product

Feature Type CDS
Coding Frame 1
Product Name
beta-lactamase/D-alanine carboxypeptidase
Synonyms
Evidence for Translation
Charge (pH 7) 1.64
Kyte-Doolittle Hydrophobicity Value -0.109
Molecular Weight (kDa) 41.8
Isoelectric Point (pI) 7.76

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name Source Accession Source DB Version Target Accession Target Description Percent Identity Alignment Length E-Value
Vaborbactam DB12107 DrugBank 5.1.4 Q53IN1 Beta-lactamase 54.5 385 1.2e-117

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001588 (493 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: NZ35_RS17920
Search term: ampC

Human Homologs

References

No references are associated with this feature.