Pseudomonas sp. P179, HMPREF1224_10047
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas sp. P179
GCF_000478485.2|latest |
| Locus Tag |
HMPREF1224_10047
|
| Name |
|
| Replicon | scaffold_1 |
| Genomic location | 5047969 - 5049300 (- strand) |
Cross-References
| RefSeq | WP_003112576.1 |
| GI | 489203482 |
| NCBI Locus Tag | HMPREF1224_10047 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
porin
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -12.55 |
| Kyte-Doolittle Hydrophobicity Value | -0.466 |
| Molecular Weight (kDa) | 48.4 |
| Isoelectric Point (pI) | 4.75 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 2ODJ | MEMBRANE PROTEIN | 12/22/06 | Crystal structure of the outer membrane protein OprD from Pseudomonas aeruginosa | Pseudomonas aeruginosa | 2.9 | X-RAY DIFFRACTION | 100.0 |
| 3SY7 | MEMBRANE PROTEIN | 07/15/11 | Improved crystal structure of Pseudomonas aeruginosa OprD | Pseudomonas aeruginosa | 2.15 | X-RAY DIFFRACTION | 99.8 |
| 4FOZ | PROTEIN TRANSPORT | 06/21/12 | Crystal Structure of OccD1 (OprD) Y282R/D307H | Pseudomonas aeruginosa | 2.4 | X-RAY DIFFRACTION | 99.3 |
Drugs Targeting this Protein
Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.
| Drug Name | Source Accession | Source DB | Version | Target Accession | Target Description | Percent Identity | Alignment Length | E-Value |
| (Hydroxyethyloxy)Tri(Ethyloxy)Octane | DB04233 | DrugBank | 5.1.4 | P32722 | Porin D | 100.0 | 443 | 6.2e-259 |
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000187 (1579 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: HMPREF1224_10047
Search term: porin
|
Human Homologs
References
No references are associated with this feature.