Pseudomonas monteilii SB3078, X969_05075

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas monteilii SB3078
GCF_000510285.1|latest
Locus Tag
X969_05075
Name
Replicon chromosome
Genomic location 1078527 - 1079603 (- strand)

Cross-References

RefSeq YP_008953379.1
GI 568180851
Entrez 17997658
NCBI Locus Tag X969_05075

Product

Feature Type CDS
Coding Frame 1
Product Name
dTDP-glucose 4,6-dehydratase
Synonyms
Evidence for Translation
Charge (pH 7) -16.71
Kyte-Doolittle Hydrophobicity Value -0.439
Molecular Weight (kDa) 40393.6
Isoelectric Point (pI) 4.89

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name Source Accession Source DB Version Target Accession Target Description Percent Identity Alignment Length E-Value
2'deoxy-Thymidine-5'-Diphospho-Alpha-D-Glucose DB03751 DrugBank 5.1.4 P26391 dTDP-glucose 4,6-dehydratase 73.0 363 5.6e-157

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 645 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004752 (533 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: X969_05075

Human Homologs

Ensembl 110, assembly GRCh38.p14
UDP-galactose-4-epimerase [Source:HGNC Symbol;Acc:HGNC:4116]
E-value: 2.1e-12
Percent Identity: 26.2
Ensembl 110, assembly GRCh38.p14
UDP-galactose-4-epimerase [Source:HGNC Symbol;Acc:HGNC:4116]
E-value: 2.1e-12
Percent Identity: 26.2

References

No references are associated with this feature.