Pseudomonas aeruginosa PAO1, PA4987

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4987
Name
Replicon chromosome
Genomic location 5603173 - 5603772 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs
CommentPA4982 negatively regulates the expression of PA4985 and PA4986[PMID:33436508]

Cross-References

RefSeq NP_253674.1
GI 15600180
Affymetrix PA4987_at
DNASU PaCD00008154
Entrez 879016
GenBank AAG08372.1
INSDC AAG08372.1
NCBI Locus Tag PA4987
protein_id(GenBank) gb|AAG08372.1|AE004911_7|gnl|PseudoCAP|PA4987
TIGR NTL03PA04988
UniParc UPI00000C5EB0
UniProtKB Acc Q9HUH8
UniProtKB ID Q9HUH8_PSEAE
UniRef100 UniRef100_A0A0A8RIK1
UniRef50 UniRef50_Q4KD74
UniRef90 UniRef90_A0A086BTP2

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -4.56
Kyte-Doolittle Hydrophobicity Value -0.452
Molecular Weight (kDa) 22.4
Isoelectric Point (pI) 5.59

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 319 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000519 (777 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4987

Human Homologs

References

Transcription Inhibitors with XRE DNA-Binding and Cupin Signal-Sensing Domains Drive Metabolic Diversification in Pseudomonas.
Trouillon J, Ragno M, Simon V, Attrée I, Elsen S
mSystems 2021 Jan 12;6(1)
PubMed ID: 33436508