Pseudomonas aeruginosa PAO1, PA4983

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4983
Name
Synonym: dmsR
Replicon chromosome
Genomic location 5598308 - 5599042 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_253670.1
GI 15600176
Affymetrix PA4983_at
Entrez 880341
GenBank AAG08368.1
INSDC AAG08368.1
NCBI Locus Tag PA4983
protein_id(GenBank) gb|AAG08368.1|AE004911_3|gnl|PseudoCAP|PA4983
TIGR NTL03PA04984
UniParc UPI00000C5EAC
UniProtKB Acc Q9HUI2
UniProtKB ID ARUR_PSEAE
UniRef100 UniRef100_Q9HUI2
UniRef50 UniRef50_Q9HUI2
UniRef90 UniRef90_Q9HUI2

Product

Feature Type CDS
Coding Frame 1
Product Name
probable two-component response regulator
Product Name Confidence: Class 3
Synonyms DmsR
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -4.67
Kyte-Doolittle Hydrophobicity Value -0.190
Molecular Weight (kDa) 27.2
Isoelectric Point (pI) 5.67

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 617 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004596 (358 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4983

Human Homologs

References

The dmsR gene encoding a dimethyl sulfoxide-responsive regulator for expression of dmsCBA (dimethyl sulfoxide respiration genes) in Rhodobacter sphaeroides f. sp. denitrificans.
Ujiiye T, Yamamoto I, Satoh T
Biochim Biophys Acta 1997 Jul 17;1353(1):84-92
PubMed ID: 9256068