Pseudomonas aeruginosa PAO1, PA4860

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4860
Name
Replicon chromosome
Genomic location 5459450 - 5460529 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253547.1
GI 15600053
Affymetrix PA4860_at
Entrez 880869
GenBank AAG08245.1
INSDC AAG08245.1
NCBI Locus Tag PA4860
protein_id(GenBank) gb|AAG08245.1|AE004899_6|gnl|PseudoCAP|PA4860
TIGR NTL03PA04861
UniParc UPI00000C5E42
UniProtKB Acc Q9HUV3
UniProtKB ID Q9HUV3_PSEAE
UniRef100 UniRef100_W0Z0U1
UniRef50 UniRef50_Q2SYF1
UniRef90 UniRef90_A6VCW7

Product

Feature Type CDS
Coding Frame 1
Product Name
probable permease of ABC transporter
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) 11.82
Kyte-Doolittle Hydrophobicity Value 0.738
Molecular Weight (kDa) 38.9
Isoelectric Point (pI) 10.00

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 398 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004489 (532 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4860

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295