Pseudomonas sp. LAMO17WK12:I4, D885_RS0108100
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas sp. LAMO17WK12:I4
GCF_000514355.1|latest |
| Locus Tag |
D885_RS0108100
|
| Name |
|
| Replicon | scaffold00004.4_C |
| Genomic location | 251066 - 252418 (+ strand) |
Cross-References
| RefSeq | WP_025753925.1 |
| GI | 647315910 |
| EC Number | 5.5.1.2 |
| NCBI Locus Tag | D885_RS0108100 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
3-carboxy-cis,cis-muconate cycloisomerase
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -5.29 |
| Kyte-Doolittle Hydrophobicity Value | 0.058 |
| Molecular Weight (kDa) | 48.1 |
| Isoelectric Point (pI) | 6.41 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 1RE5 | ISOMERASE | 11/06/03 | Crystal structure of 3-carboxy-cis,cis-muconate lactonizing enzyme from Pseudomonas putida | Pseudomonas putida | 2.6 | X-RAY DIFFRACTION | 97.1 |
Drugs Targeting this Protein
Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.
| Drug Name | Source Accession | Source DB | Version | Target Accession | Target Description | Percent Identity | Alignment Length | E-Value |
| 1,4-Dithiothreitol | DB04447 | DrugBank | 5.1.4 | P32427 | 3-carboxy-cis,cis-muconate cycloisomerase | 95.3 | 422 | 1.4e-220 |
| Citric acid | DB04272 | DrugBank | 5.1.4 | P32427 | 3-carboxy-cis,cis-muconate cycloisomerase | 95.3 | 422 | 1.4e-220 |
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000229 (504 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: D885_RS0108100
Search term: 3-carboxy-cis,cis-muconate cycloisomerase
|
Human Homologs
References
No references are associated with this feature.