Pseudomonas syringae BRIP39023, A988_24649 (ligA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00278
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01588
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01588
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003911 DNA ligase (NAD+) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00532
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Hamap MF_01588 DNA ligase [ligA]. IPR001679 NAD-dependent DNA ligase 2 779 51.075485
FunFam G3DSA:1.10.150.20:FF:000007 DNA ligase - - 449 524 1.8E-28
Coils Coil Coil - - 1 21 -
NCBIfam TIGR00575 JCVI: DNA ligase (NAD(+)) LigA IPR001679 NAD-dependent DNA ligase 11 605 0.0
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 612 696 1.24E-12
FunFam G3DSA:2.40.50.140:FF:000012 DNA ligase - - 324 397 2.0E-34
FunFam G3DSA:3.30.470.30:FF:000001 DNA ligase - - 65 322 1.2E-106
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 326 406 1.88E-27
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 324 397 5.6E-32
FunFam G3DSA:1.10.287.610:FF:000002 DNA ligase - - 1 64 1.4E-27
PIRSF PIRSF001604 LigA IPR001679 NAD-dependent DNA ligase 1 623 0.0
SMART SM00292 BRCT_7 IPR001357 BRCT domain 705 782 8.6E-7
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 411 596 4.82E-49
SUPERFAMILY SSF56091 DNA ligase/mRNA capping enzyme, catalytic domain - - 3 323 3.42E-117
Gene3D G3DSA:1.10.150.20 - - - 524 605 2.3E-22
SUPERFAMILY SSF52113 BRCT domain IPR036420 BRCT domain superfamily 705 779 3.36E-16
Gene3D G3DSA:3.30.470.30 DNA ligase/mRNA capping enzyme - - 65 322 4.8E-99
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 531 550 140.0
CDD cd17748 BRCT_DNA_ligase_like - - 708 777 2.37993E-22
Pfam PF00533 BRCA1 C Terminus (BRCT) domain IPR001357 BRCT domain 705 777 1.7E-9
Pfam PF12826 Helix-hairpin-helix motif IPR041663 DisA/LigA, helix-hairpin-helix motif 529 592 9.0E-20
Gene3D G3DSA:1.10.150.20 - - - 618 692 3.5E-10
Gene3D G3DSA:1.10.150.20 - - - 449 523 9.4E-27
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 499 518 950.0
Pfam PF14520 Helix-hairpin-helix domain - - 465 518 0.0055
Gene3D G3DSA:3.40.50.10190 BRCT domain IPR036420 BRCT domain superfamily 693 781 9.1E-23
Gene3D G3DSA:1.10.287.610 Helix hairpin bin - - 1 64 4.5E-27
Pfam PF03120 NAD-dependent DNA ligase OB-fold domain IPR004150 NAD-dependent DNA ligase, OB-fold 329 405 3.2E-34
Pfam PF01653 NAD-dependent DNA ligase adenylation domain IPR013839 NAD-dependent DNA ligase, adenylation 4 324 7.3E-127
Gene3D G3DSA:6.20.10.30 - - - 398 448 9.4E-13
CDD cd00114 LIGANc IPR013839 NAD-dependent DNA ligase, adenylation 6 324 0.0
Pfam PF12826 Helix-hairpin-helix motif IPR041663 DisA/LigA, helix-hairpin-helix motif 626 680 8.3E-8
PANTHER PTHR23389 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 - - 17 764 9.2E-50
SMART SM00532 ligaN3 IPR013840 NAD-dependent DNA ligase, N-terminal 3 467 0.0
PIRSF PIRSF001604 LigA IPR001679 NAD-dependent DNA ligase 612 784 5.7E-31
Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type 414 453 4.8E-11
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 465 484 1.8
FunFam G3DSA:1.10.150.20:FF:000006 DNA ligase - - 525 602 1.4E-22

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.