Pseudomonas aeruginosa 19BR, IAI_RS0131180

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd02888
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd02888
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0031419 cobalamin binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd02888
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 528 555 2.6E-18
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 197 216 2.6E-18
CDD cd02888 RNR_II_dimer IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent 95 671 0.0
Pfam PF02867 Ribonucleotide reductase, barrel domain IPR000788 Ribonucleotide reductase large subunit, C-terminal 123 669 0.0
SUPERFAMILY SSF51998 PFL-like glycyl radical enzymes - - 35 710 0.0
PANTHER PTHR43371 VITAMIN B12-DEPENDENT RIBONUCLEOTIDE REDUCTASE - - 15 725 0.0
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 412 434 2.6E-18
NCBIfam TIGR02504 JCVI: adenosylcobalamin-dependent ribonucleoside-diphosphate reductase IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent 43 678 0.0
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 336 347 2.6E-18
Gene3D G3DSA:3.20.70.20 - - - 14 672 0.0
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 374 397 2.6E-18
FunFam G3DSA:3.20.70.20:FF:000040 Vitamin B12-dependent ribonucleotide reductase - - 14 672 0.0
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 440 463 2.6E-18

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.