Pseudomonas aeruginosa 19BR, IAI_RS0108470

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004673 protein histidine kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02702
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00082
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02702
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02702
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00082
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF55781 GAF domain-like - - 495 637 3.05E-5
CDD cd00075 HATPase - - 767 870 6.47675E-33
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 858 871 8.1E-14
FunFam G3DSA:1.10.287.130:FF:000027 Sensor histidine kinase KdpD - - 645 717 1.7E-42
SUPERFAMILY SSF52402 Adenine nucleotide alpha hydrolases-like - - 248 358 1.05E-13
Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal 19 227 9.7E-91
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 733 878 5.2E-35
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 708 876 1.57E-37
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 799 813 8.1E-14
FunFam G3DSA:3.40.50.300:FF:000483 Sensor histidine kinase KdpD - - 16 226 2.3E-99
PANTHER PTHR45569 SENSOR PROTEIN KDPD - - 2 876 0.0
Gene3D G3DSA:1.10.287.130 - - - 645 717 8.8E-18
Coils Coil Coil - - 692 712 -
Gene3D G3DSA:3.30.450.40 - IPR029016 GAF-like domain superfamily 501 644 1.2E-23
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 817 827 8.1E-14
SUPERFAMILY SSF47384 Homodimeric domain of signal transducing histidine kinase IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily 646 719 1.9E-16
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 762 874 1.5E-32
Pfam PF00582 Universal stress protein family IPR006016 UspA 248 358 2.6E-11
SMART SM00388 HisKA_10 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 650 718 1.2E-17
CDD cd00082 HisKA IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 648 714 7.21477E-15
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 833 851 8.1E-14
Pfam PF13493 Domain of unknown function (DUF4118) IPR025201 Sensor protein KdpD, transmembrane domain 390 494 2.5E-26
CDD cd01987 USP_OKCHK - - 248 365 1.62601E-32
Pfam PF00512 His Kinase A (phospho-acceptor) domain IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 651 718 5.6E-14
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 16 226 3.2E-98
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 767 873 2.0E-22
Gene3D G3DSA:1.20.120.620 Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd, IPR038318 KdpD, transmembrane domain superfamily 385 489 2.0E-27
FunFam G3DSA:3.30.565.10:FF:000042 Two-component sensor histidine kinase KdpD - - 722 876 6.3E-46
Gene3D G3DSA:3.40.50.620 HUPs IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 229 361 1.3E-14

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.