Pseudomonas psychrotolerans L19, PPL19_19467 (ligA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03119
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00278
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003911 DNA ligase (NAD+) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00532
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00278
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00533 BRCA1 C Terminus (BRCT) domain IPR001357 BRCT domain 714 787 4.3E-12
PANTHER PTHR23389 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 - - 7 772 1.6E-51
SMART SM00532 ligaN3 IPR013840 NAD-dependent DNA ligase, N-terminal 6 473 0.0
CDD cd00114 LIGANc IPR013839 NAD-dependent DNA ligase, adenylation 9 330 0.0
NCBIfam TIGR00575 JCVI: DNA ligase (NAD(+)) LigA IPR001679 NAD-dependent DNA ligase 14 618 0.0
Gene3D G3DSA:3.30.470.30 DNA ligase/mRNA capping enzyme - - 69 328 6.3E-98
SMART SM00292 BRCT_7 IPR001357 BRCT domain 714 791 5.2E-12
FunFam G3DSA:3.30.470.30:FF:000001 DNA ligase - - 68 328 1.8E-105
FunFam G3DSA:1.10.287.610:FF:000002 DNA ligase - - 2 67 6.1E-28
FunFam G3DSA:2.40.50.140:FF:000012 DNA ligase - - 330 403 9.3E-35
Gene3D G3DSA:1.10.287.610 Helix hairpin bin - - 1 68 4.6E-27
Gene3D G3DSA:3.40.50.10190 BRCT domain IPR036420 BRCT domain superfamily 704 790 1.4E-25
PIRSF PIRSF001604 LigA IPR001679 NAD-dependent DNA ligase 1 621 0.0
Gene3D G3DSA:1.10.150.20 - - - 623 703 2.1E-5
FunFam G3DSA:1.10.150.20:FF:000007 DNA ligase - - 455 530 5.9E-30
Pfam PF12826 Helix-hairpin-helix motif IPR041663 DisA/LigA, helix-hairpin-helix motif 535 598 1.2E-19
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 505 524 450.0
FunFam G3DSA:1.10.150.20:FF:000006 DNA ligase - - 531 608 2.0E-23
PIRSF PIRSF001604 LigA IPR001679 NAD-dependent DNA ligase 616 793 7.3E-30
SUPERFAMILY SSF52113 BRCT domain IPR036420 BRCT domain superfamily 715 790 2.24E-18
Pfam PF03120 NAD-dependent DNA ligase OB-fold domain IPR004150 NAD-dependent DNA ligase, OB-fold 335 411 7.2E-35
CDD cd17748 BRCT_DNA_ligase_like - - 717 787 7.60023E-27
Pfam PF01653 NAD-dependent DNA ligase adenylation domain IPR013839 NAD-dependent DNA ligase, adenylation 7 331 1.7E-125
SUPERFAMILY SSF56091 DNA ligase/mRNA capping enzyme, catalytic domain - - 4 329 1.8E-116
Hamap MF_01588 DNA ligase [ligA]. IPR001679 NAD-dependent DNA ligase 5 788 53.118378
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 417 608 2.26E-53
Gene3D G3DSA:1.10.150.20 - - - 530 610 1.4E-25
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 331 413 5.48E-28
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 624 706 3.34E-5
Gene3D G3DSA:1.10.150.20 - - - 455 529 4.2E-28
Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type 420 459 1.3E-12
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 471 490 130.0
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 569 588 690.0
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 537 556 57.0
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 330 403 1.3E-32
Gene3D G3DSA:6.20.10.30 - - - 404 454 1.2E-13

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.