Pseudomonas aeruginosa PACS2, A0K_RS13015

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00448
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00082
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00082
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Two-component regulatory systems Other PACS2 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 445 557 4.5E-10
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 257 422 1.01E-36
CDD cd00130 PAS IPR000014 PAS domain 55 156 0.00313059
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 311 422 1.2E-27
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 448 557 1.3E-11
Gene3D G3DSA:1.10.287.130 - - - 166 265 3.9E-13
CDD cd00156 REC - - 448 547 7.67414E-18
Pfam PF13188 PAS domain IPR000014 PAS domain 44 102 1.8E-4
Coils Coil Coil - - 28 48 -
SMART SM00388 HisKA_10 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 202 267 2.2E-8
FunFam G3DSA:3.30.450.20:FF:000184 Hybrid sensor histidine kinase/response regulator - - 39 155 1.1E-71
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 347 361 3.7E-10
Coils Coil Coil - - 157 202 -
FunFam G3DSA:3.30.565.10:FF:000049 Two-component sensor histidine kinase - - 269 423 3.2E-54
NCBIfam TIGR00229 JCVI: PAS domain S-box protein IPR000014 PAS domain 40 164 8.5E-10
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 269 423 1.6E-34
Gene3D G3DSA:3.30.450.20 PAS domain - - 39 155 1.0E-14
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 382 400 3.7E-10
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 406 419 3.7E-10
Gene3D G3DSA:3.40.50.2300 - - - 445 564 4.1E-18
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 443 562 7.4E-21
SUPERFAMILY SSF55785 PYP-like sensor domain (PAS domain) IPR035965 PAS domain superfamily 30 155 2.27E-12
PANTHER PTHR43047 TWO-COMPONENT HISTIDINE PROTEIN KINASE - - 29 560 3.0E-68
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 312 420 2.1E-19
CDD cd00082 HisKA IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 200 263 3.46511E-7
SUPERFAMILY SSF47384 Homodimeric domain of signal transducing histidine kinase IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily 185 266 2.75E-11
FunFam G3DSA:1.10.287.130:FF:000081 Hybrid sensor histidine kinase/response regulator - - 169 265 1.8E-40

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.