Pseudomonas aeruginosa PACS2, A0K_RS06550

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:1.10.1040.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051287 NAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01692
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0050661 NADP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03446
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008442 3-hydroxyisobutyrate dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01692
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Carbon compound catabolism Other PACS2 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase IPR029154 3-hydroxyisobutyrate dehydrogenase-like, NAD-binding domain 165 291 2.1E-34
SUPERFAMILY SSF48179 6-phosphogluconate dehydrogenase C-terminal domain-like IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily 164 293 1.81E-41
Gene3D G3DSA:3.40.50.720 - - - 1 163 2.4E-60
Gene3D G3DSA:1.10.1040.10 - IPR013328 6-phosphogluconate dehydrogenase, domain 2 164 298 1.2E-48
PIRSF PIRSF000103 HIBADH IPR015815 3-hydroxyisobutyrate dehydrogenase-related 1 298 2.1E-83
PANTHER PTHR22981 3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED - - 1 293 5.0E-116
Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase IPR006115 6-phosphogluconate dehydrogenase, NADP-binding 3 162 4.6E-53
NCBIfam TIGR01692 JCVI: 3-hydroxyisobutyrate dehydrogenase IPR011548 3-hydroxyisobutyrate dehydrogenase 6 292 6.8E-125
FunFam G3DSA:1.10.1040.10:FF:000006 3-hydroxyisobutyrate dehydrogenase - - 165 297 1.0E-52
FunFam G3DSA:3.40.50.720:FF:000071 2-hydroxy-3-oxopropionate reductase - - 1 164 2.5E-66
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 1 162 2.15E-49

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.