Pseudomonas aeruginosa NCGM2.S1, NCGM2_RS15410 (ligD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01068
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003910 DNA ligase (ATP) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01068
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01068
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006310 DNA recombination
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01068
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pnc03450 Non-homologous end-joining 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.30.470.30 DNA ligase/mRNA capping enzyme - - 241 356 2.9E-46
SUPERFAMILY SSF56091 DNA ligase/mRNA capping enzyme, catalytic domain - - 216 399 7.67E-45
NCBIfam TIGR02779 JCVI: non-homologous end-joining DNA ligase, ligase domain IPR014146 DNA ligase D, ligase domain 219 521 6.3E-110
MobiDBLite mobidb-lite consensus disorder prediction - - 1 32 -
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 402 523 8.1E-37
PANTHER PTHR42705 BIFUNCTIONAL NON-HOMOLOGOUS END JOINING PROTEIN LIGD - - 228 836 9.7E-111
Gene3D G3DSA:3.30.1490.70 - - - 229 397 2.9E-46
Gene3D G3DSA:3.90.920.10 DNA primase, PRIM domain - - 556 840 2.7E-92
Pfam PF13298 DNA polymerase Ligase (LigD) IPR014144 DNA ligase D, 3'-phosphoesterase domain 40 144 4.6E-39
NCBIfam TIGR02777 JCVI: DNA ligase D, 3'-phosphoesterase domain IPR014144 DNA ligase D, 3'-phosphoesterase domain 7 162 1.4E-70
MobiDBLite mobidb-lite consensus disorder prediction - - 515 539 -
NCBIfam TIGR02778 JCVI: non-homologous end-joining DNA ligase, polymerase domain IPR014145 DNA ligase D, polymerase domain 549 793 2.7E-88
CDD cd07971 OBF_DNA_ligase_LigD - - 403 520 1.43276E-49
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 403 523 3.98E-28
CDD cd04862 PaeLigD_Pol_like IPR033651 LigD polymerase domain, PaeLigD-type 566 792 5.02831E-127
Pfam PF04679 ATP dependent DNA ligase C terminal region IPR012309 DNA ligase, ATP-dependent, C-terminal 418 515 1.2E-23
Pfam PF01068 ATP dependent DNA ligase domain IPR012310 DNA ligase, ATP-dependent, central 224 399 5.1E-22
NCBIfam TIGR02776 JCVI: DNA ligase D IPR014143 DNA ligase D 228 823 0.0
CDD cd07906 Adenylation_DNA_ligase_LigD_LigC - - 217 400 2.00909E-79
MobiDBLite mobidb-lite consensus disorder prediction - - 8 32 -

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.