Pseudomonas sp. PTA1, EW80_RS16610

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00278
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003911 DNA ligase (NAD+) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF001604
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF001604
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF001604
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SMART SM00532 ligaN3 IPR013840 NAD-dependent DNA ligase, N-terminal 3 467 0.0
Gene3D G3DSA:1.10.287.610 Helix hairpin bin - - 1 64 1.6E-27
FunFam G3DSA:1.10.287.610:FF:000002 DNA ligase - - 1 64 8.4E-29
Pfam PF00533 BRCA1 C Terminus (BRCT) domain IPR001357 BRCT domain 705 774 1.5E-6
FunFam G3DSA:1.10.150.20:FF:000007 DNA ligase - - 449 524 1.6E-28
FunFam G3DSA:3.30.470.30:FF:000001 DNA ligase - - 65 322 7.5E-108
CDD cd17748 BRCT_DNA_ligase_like - - 707 777 5.40738E-23
Gene3D G3DSA:3.40.50.10190 BRCT domain IPR036420 BRCT domain superfamily 705 785 4.8E-22
Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type 415 453 9.0E-11
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 326 407 1.08E-27
SUPERFAMILY SSF52113 BRCT domain IPR036420 BRCT domain superfamily 705 779 3.18E-16
NCBIfam TIGR00575 JCVI: DNA ligase (NAD(+)) LigA IPR001679 NAD-dependent DNA ligase 11 609 0.0
Gene3D G3DSA:6.20.10.30 - - - 398 448 4.6E-13
FunFam G3DSA:2.40.50.140:FF:000012 DNA ligase - - 324 397 2.3E-34
Pfam PF14520 Helix-hairpin-helix domain - - 465 519 0.0061
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 531 550 140.0
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 324 397 2.8E-32
Pfam PF12826 Helix-hairpin-helix motif IPR041663 DisA/LigA, helix-hairpin-helix motif 529 592 3.0E-19
Gene3D G3DSA:1.10.150.20 - - - 449 523 6.4E-28
Pfam PF01653 NAD-dependent DNA ligase adenylation domain IPR013839 NAD-dependent DNA ligase, adenylation 4 324 1.6E-127
Gene3D G3DSA:1.10.150.20 - - - 617 695 2.1E-10
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 611 695 4.08E-13
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 499 518 870.0
Hamap MF_01588 DNA ligase [ligA]. IPR001679 NAD-dependent DNA ligase 2 778 51.447975
Gene3D G3DSA:3.30.470.30 DNA ligase/mRNA capping enzyme - - 65 322 1.0E-99
PIRSF PIRSF001604 LigA IPR001679 NAD-dependent DNA ligase 611 783 3.2E-30
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 411 603 3.26E-52
Pfam PF03120 NAD-dependent DNA ligase OB-fold domain IPR004150 NAD-dependent DNA ligase, OB-fold 329 405 2.7E-34
Gene3D G3DSA:1.10.150.20 - - - 524 605 1.5E-23
SUPERFAMILY SSF56091 DNA ligase/mRNA capping enzyme, catalytic domain - - 2 324 2.52E-117
SMART SM00292 BRCT_7 IPR001357 BRCT domain 704 781 3.7E-6
Pfam PF12826 Helix-hairpin-helix motif IPR041663 DisA/LigA, helix-hairpin-helix motif 625 680 5.2E-8
FunFam G3DSA:1.10.150.20:FF:000006 DNA ligase - - 525 602 6.5E-23
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 465 484 6.8
PIRSF PIRSF001604 LigA IPR001679 NAD-dependent DNA ligase 1 621 0.0
CDD cd00114 LIGANc IPR013839 NAD-dependent DNA ligase, adenylation 6 324 0.0
PANTHER PTHR23389 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 - - 17 761 2.6E-48

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.