Pseudomonas sp. MRSN12121, TO66_RS09730

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003911 DNA ligase (NAD+) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03119
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03119
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03119
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00278
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG psem03030 DNA replication 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psem03420 Nucleotide excision repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psem03410 Base excision repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psem03430 Mismatch repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.40.50.10190 BRCT domain IPR036420 BRCT domain superfamily 691 782 1.4E-22
FunFam G3DSA:3.30.470.30:FF:000001 DNA ligase - - 65 322 3.3E-106
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 324 397 6.6E-33
PANTHER PTHR23389 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 - - 17 764 1.7E-49
Gene3D G3DSA:6.20.10.30 - - - 398 448 1.4E-12
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 411 597 2.15E-51
Coils Coil Coil - - 1 21 -
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 531 550 140.0
CDD cd00114 LIGANc IPR013839 NAD-dependent DNA ligase, adenylation 6 324 0.0
Pfam PF12826 Helix-hairpin-helix motif IPR041663 DisA/LigA, helix-hairpin-helix motif 529 592 6.2E-20
Gene3D G3DSA:1.10.150.20 - - - 524 606 9.1E-22
Gene3D G3DSA:1.10.150.20 - - - 623 678 3.1E-7
Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type 414 453 4.9E-11
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 614 699 4.82E-10
SMART SM00532 ligaN3 IPR013840 NAD-dependent DNA ligase, N-terminal 3 467 0.0
Pfam PF01653 NAD-dependent DNA ligase adenylation domain IPR013839 NAD-dependent DNA ligase, adenylation 4 324 1.2E-125
Pfam PF14520 Helix-hairpin-helix domain - - 465 519 0.0057
Pfam PF03120 NAD-dependent DNA ligase OB-fold domain IPR004150 NAD-dependent DNA ligase, OB-fold 329 405 6.6E-35
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 465 484 1.8
Pfam PF00533 BRCA1 C Terminus (BRCT) domain IPR001357 BRCT domain 707 778 1.3E-9
FunFam G3DSA:2.40.50.140:FF:000012 DNA ligase - - 324 397 8.5E-35
SUPERFAMILY SSF56091 DNA ligase/mRNA capping enzyme, catalytic domain - - 2 324 2.88E-117
PIRSF PIRSF001604 LigA IPR001679 NAD-dependent DNA ligase 614 785 6.7E-29
CDD cd17748 BRCT_DNA_ligase_like - - 710 777 1.89791E-23
Gene3D G3DSA:3.30.470.30 DNA ligase/mRNA capping enzyme - - 65 322 2.7E-99
SMART SM00292 BRCT_7 IPR001357 BRCT domain 707 784 2.8E-7
Gene3D G3DSA:1.10.287.610 Helix hairpin bin - - 1 64 6.8E-28
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 499 518 630.0
PIRSF PIRSF001604 LigA IPR001679 NAD-dependent DNA ligase 1 624 0.0
Hamap MF_01588 DNA ligase [ligA]. IPR001679 NAD-dependent DNA ligase 2 781 51.584755
FunFam G3DSA:1.10.287.610:FF:000002 DNA ligase - - 1 64 5.4E-29
SUPERFAMILY SSF52113 BRCT domain IPR036420 BRCT domain superfamily 708 782 1.78E-16
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 326 407 4.45E-28
Gene3D G3DSA:1.10.150.20 - - - 449 523 1.9E-28
NCBIfam TIGR00575 JCVI: DNA ligase (NAD(+)) LigA IPR001679 NAD-dependent DNA ligase 11 596 0.0
FunFam G3DSA:1.10.150.20:FF:000007 DNA ligase - - 449 524 5.1E-30

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.