Pseudomonas sp. 11/12A, GQ39_RS09665

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0030976 thiamine pyrophosphate binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00205
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02775
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000287 magnesium ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00205
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd07035 TPP_PYR_POX_like - - 10 166 2.71435E-59
Pfam PF00205 Thiamine pyrophosphate enzyme, central domain IPR012000 Thiamine pyrophosphate enzyme, central domain 197 325 1.5E-26
SUPERFAMILY SSF52467 DHS-like NAD/FAD-binding domain IPR029035 DHS-like NAD/FAD-binding domain superfamily 160 351 1.71E-36
Gene3D G3DSA:3.40.50.1220 - - - 192 356 4.1E-36
SUPERFAMILY SSF52518 Thiamin diphosphate-binding fold (THDP-binding) IPR029061 Thiamin diphosphate-binding fold 362 533 1.52E-40
FunFam G3DSA:3.40.50.970:FF:000007 Acetolactate synthase - - 1 185 8.1E-49
PANTHER PTHR18968 THIAMINE PYROPHOSPHATE ENZYMES IPR045229 Thiamine pyrophosphate enzyme 5 529 1.8E-120
Gene3D G3DSA:3.40.50.970 - - - 1 181 1.2E-54
Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain 7 175 2.8E-53
Gene3D G3DSA:3.40.50.970 - - - 360 533 2.9E-38
Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain IPR011766 Thiamine pyrophosphate enzyme, TPP-binding 390 528 3.4E-27
CDD cd00568 TPP_enzymes - - 364 530 6.5422E-42
SUPERFAMILY SSF52518 Thiamin diphosphate-binding fold (THDP-binding) IPR029061 Thiamin diphosphate-binding fold 5 179 3.39E-53

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.