Pseudomonas simiae MEB105, RU03_RS12595

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004673 protein histidine kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF50341
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006935 chemotaxis
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:1.20.120.160
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 1463 1649 1.6E-51
CDD cd17546 REC_hyHK_CKI1_RcsC-like - - 1815 1926 5.3237E-32
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 431 553 3.14E-13
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 747 869 5.5E-19
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 747 843 0.02
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 742 873 1.5E-18
SUPERFAMILY SSF50341 CheW-like IPR036061 CheW-like domain superfamily 1649 1782 3.14E-23
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 617 740 4.1E-22
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 1815 1926 2.2E-27
Gene3D G3DSA:2.30.30.40 SH3 Domains - - 1723 1784 2.0E-19
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 10 98 3.6E-8
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1180 1300 1.83E-28
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1180 1309 1.4E-31
PANTHER PTHR43395 SENSOR HISTIDINE KINASE CHEA - - 619 739 0.0
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 1610 1628 7.9E-10
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 616 738 2.22E-21
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 619 706 3.8E-13
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1182 1276 1.1E-15
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 1812 1930 3.27E-37
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 617 709 2.24702E-10
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 884 1012 1.7E-11
MobiDBLite mobidb-lite consensus disorder prediction - - 583 599 -
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1180 1278 1.81073E-13
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 617 710 3.7E-6
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 750 834 2.4E-11
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1044 1114 3.2E-12
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 1509 1650 1.4E-21
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 1466 1647 1.26E-35
FunFam G3DSA:3.30.565.10:FF:000016 Chemotaxis protein CheA, putative - - 1465 1649 5.9E-60
Gene3D G3DSA:3.40.50.2300 - - - 1815 1934 1.7E-40
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 7 129 1.05E-18
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1041 1174 4.0E-26
SMART SM01231 H_kinase_dim_2 IPR004105 Histidine kinase CheA-like, homodimeric domain 1325 1464 2.8E-11
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 1513 1649 1.2E-13
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1042 1139 0.013
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 750 807 5.88774E-5
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 15 122 8.0E-9
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 1554 1568 7.9E-10
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1042 1140 5.00787E-11
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 883 1005 4.41E-13
MobiDBLite mobidb-lite consensus disorder prediction - - 583 612 -
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 1634 1647 7.9E-10
Pfam PF01584 CheW-like domain IPR002545 CheW-like domain 1655 1787 5.5E-20
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 1813 1926 3.2E-36
Coils Coil Coil - - 1356 1383 -
SMART SM00260 chew_2 IPR002545 CheW-like domain 1642 1786 2.4E-27
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1180 1277 8.9E-9
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1042 1164 2.36E-25

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.