Pseudomonas chlororaphis subsp. aureofaciens NBRC 3521, PCH03S_RS23580 (ampC)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas chlororaphis subsp. aureofaciens NBRC 3521
GCF_000813225.1|latest |
| Locus Tag |
PCH03S_RS23580
|
| Name |
ampC
|
| Replicon | contig_40 |
| Genomic location | 155733 - 156923 (+ strand) |
Cross-References
| RefSeq | WP_041988286.1 |
| GI | 754598291 |
| EC Number | 3.5.2.6 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
class C beta-lactamase
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | 2.64 |
| Kyte-Doolittle Hydrophobicity Value | -0.126 |
| Molecular Weight (kDa) | 42.6 |
| Isoelectric Point (pI) | 8.31 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Drugs Targeting this Protein
Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.
| Drug Name | Source Accession | Source DB | Version | Target Accession | Target Description | Percent Identity | Alignment Length | E-Value |
| Cefotaxime | DB00493 | DrugBank | 5.1.4 | B2ZTR6 | Beta-lactamase | 46.1 | 362 | 2.8e-92 |
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG001588 (493 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PCH03S_RS23580
Search term: ampC
Search term: class C beta-lactamase
|
Human Homologs
References
No references are associated with this feature.